The departments of Guizhou University are: Humanities College, Law School, Science College, Foreign Languages College, Economics College, Computer Science and Information College, Management College, Agricultural College, Life Science College, Forestry College, Animal Science College, Civil Engineering College, Mining College, Mechanical Engineering College, Materials and Metallurgy College, Resources and Environmental Engineering College, Vocational and Technical College, Electrical Engineering College, Chemical Engineering College, Mingde College and Art College.

The main institutions are the Faculty of Arts, the School of Law, the School of Management, the School of Pharmacy and the School of Mining.