Dezhou No.1 Middle School is one of the first batch of 19 key middle schools in Shandong Province, a provincial-level standardized school and an advanced unit of spiritual civilization.

Dezhou No.1 Middle School was founded in 1929, formerly known as Provincial No.12 Middle School. 1933 was renamed Lide County Junior High School, and 1938 was renamed Dezhou No.1 Middle School.

As of April 20 15, Dezhou No.1 Middle School has two campuses: the old campus in Decheng District and the new campus in Economic Development Zone. The school covers an area of 345 mu with a building area of 200,000 square meters. There are 476 faculty members, 103 classes and 5875 students.