This book is recommended by the Graduate Work Office of the Ministry of Education, and it is also a reference book at the same level, that is, an advanced course in immunology. This book is divided into three parts (immune system, immune response and immunopathology) and 18 chapters, including an overview of immunology, immune cells, immunoglobulin and its coding genes, major histocompatibility complexes, cytokines, differentiation and adhesion molecular clusters, innate immunity, T cell recognition antigens, T cell activation, B cell activation, immune response mechanism, immune regulation, hypersensitivity, anti-infection immunity and so on. In content, both foundation and progress are equally important. While introducing the basic concepts, we pay attention to the introduction of new knowledge, which makes the whole book systematic, scientific and forward-looking.