1. control the source of infection, improve the epidemic situation report, and eradicate malaria patients and those with plasmodium.

2. Cutting off the route of transmission is mainly to eliminate Anopheles and prevent being bitten by Anopheles. Clear the breeding ground of Anopheles larvae and use insecticidal drugs. Personal protection can use insect repellent or mosquito net to avoid being bitten by mosquitoes.

3. Improving people's resistance to malaria vaccination may reduce the incidence and mortality of this disease, but it is very difficult to develop vaccines because of the diversity of plasmodium antigens. At present, sporozoite protein and gene vaccine are mainly developed, but they are not available for field application.

Malaria vaccine, AIDS vaccine and tuberculosis vaccine have become the top three vaccines in the world. The "recombinant malaria vaccine" independently developed by China has been approved by National Medical Products Administration and the World Health Organization, and has entered clinical trials.

Chemical drug prevention is a common measure at present. Healthy people and migrants in high malaria areas can be selected as appropriate. Commonly used chloroquine, 0.3g/ time, 1 time/week. In chloroquine-resistant malaria endemic areas, mefloquine 0.25g/ time, 1 time/week can be used. You can also choose pyrimethamine 25mg/ time, or doxycycline 0.2g/ time, 1 time/week.

Tafenquine is an 8- aminoquine antimalarial drug. A randomized, double-blind study was conducted in Ghana to prevent people with normal G6PD and pregnant women from suffering from falciparum malaria. The results showed that within 13 weeks, the preventive effect of oral administration of 25mg per week was 32%, that of 50mg group was 84%, and that of 100mg group was 87%.

Artesunate, which is widely used in the treatment of clinical cases at present, should not be used as a preventive drug for malaria, so as to avoid plasmodium becoming resistant to it and shorten its clinical application cycle.