I'm going to middle school, and the answer is not accurate. Please read the information and make your own decision. )

Rheumatoid granuloma or rheumatic corpuscles or Ashoff corpuscles have diagnostic significance.

Ashoff's corpuscles are very small and can only be seen under a microscope. Most of them are located in myocardial stroma, endocardium and subcutaneous connective tissue. Most of them are located near myocardial interstitial small vessels, which are spindle-shaped or round; The center is cellulose-like necrosis, surrounded by various cell components: Anitschkow cells: rich in cytoplasm, basophilic, large in nucleus, oval and vacuolar. Chromatin is concentrated in the center of the nucleus. The cross section of the nucleus looks like an owl's eye and the longitudinal section looks like a caterpillar. Aschoff giant cell: It contains 1-4 cystic nuclei, similar to Anitschkow cells, and its cytoplasm is basophilic. There are also a few lymphocytes and neutrophils in the small body.

Ashoff corpuscles ① spherical, oval or spindle corpuscles; ② Celluloid necrosis can be seen in the center, and there are many Ashoff cells around; ③ Infiltration of peripheral lymphocytes and plasma cells.