(1) The changes of biological rhythm and cognitive function of patients after coronary artery bypass grafting were 40,000 yuan.
(2) Research on malignant hyperthermia —— Establishment of an experimental method of human skeletal muscle contraction in vitro in China, 20,000 yuan.
(3) The basic and clinical research on the changes of patients' neuropsychological state during perioperative period is 50,000 yuan.
(2) Currently undertaking scientific research projects.
Project supported by the National Natural Science Foundation of China.
Effect of Melatonin on Neurobehavioral Disorder in Aged Rats after Anesthesia Operation and Its Molecular Mechanism (30,972,835) 320,000 yuan.
2. Projects funded by the Ministry of Personnel and Peking Union Medical College Hospital Fund:
(2) Pharmacogenomics and Individualized Postoperative Analgesia (Key Fund of Ministry of Personnel) 70,000 yuan.
(3) Influence of operation and anesthesia on postoperative cognitive behavior changes (hospital fund) 20,000 yuan.
(4) Interaction between lipid-lowering drugs and general anesthetics (Zhan Sen Science Foundation) 70,000 yuan.
(5) The establishment and clinical application of standardized laboratory diagnosis method for malignant hyperthermia was 654.38 million yuan.
(Key Project Fund of Peking Union Medical College Hospital)
3. Key Project Fund of Peking University Third Hospital
Optimization of anesthesia mode in spinal surgery: 200,000 yuan.
2. The theme of clinical drug validation
Effect of intraoperative fluid therapy with (1) hydroxyethyl starch on visceral perfusion and oxygenation;
(2) The safety and effectiveness of epidural analgesia with tetracaine hydrochloride;
(3) Clinical application of remifentanil, a new opioid drug;
(4) Application of non-steroidal anti-inflammatory drugs (lornoxicam) in postoperative analgesia;
(5) Clinical drug verification of a new desiccant (penehyclidine ether);
(6) Clinical observation of central venous catheterization rate under the guidance of P wave of electrocardiogram;
(7) Application of auditory evoked potential in monitoring anesthesia depth and awakening test in scoliosis surgery;
(two) the first author and correspondent who published papers and works.
Papers included in SCI:
1. Guo Xiangyang, Xu, Ren Hongzhi, et al. Volume substitution effect
Effect of hydroxyethyl starch solution on visceral oxygenation in surgical patients
Cytoreductive surgery for ovarian cancer. Chinese medical journal, 2003,116 (7): 996-1000. (If 0.636)
2. Guo Xiangyang, Yi Jie, Ye Tiehu, et al. Comparison of remifentanil and fentanyl in intravenous anesthesia
Patients undergoing modified radical mastectomy or total hysterectomy. TMC (Traditional Chinese Medicine)
Journal, 2003,116 (9):1386-1390. (If 0.636)
3. Guo X, Kuzumi Eiko, Susan Charman, et al. Perioperative melatonin secretion
Patients undergoing coronary artery transplantation. A paper, 2002,94 (5):1085-91. (If 2.2 14)
Foreign electronic journals:
4.x Guo, E Kuzumi, A stech, Vujil. Secretion of melatonin in patients during perioperative period.
Coronary artery bypass grafting: a preliminary study. Critical Care 200 1, 5:46-. (electronic version. This article can be found online at-) (if 3.83)
Domestic core journals: (* correspondent)
5. Guo Xiangyang *, Luo, etc. Preliminary establishment of experimental diagnosis method for malignant hyperthermia. Chinese Journal of Anesthesiology, 2008, (28):526-529.
6. Guo Xiangyang, Luo, Yin Yiqing, etc. Perioperative plasma neuron-specific enolase in patients undergoing coronary artery bypass grafting.
Relationship between chemokine concentration and postoperative cognitive function. Basic Medicine and Clinic, 2005,25 (7): 934-935.
7. Guo Xiangyang, Luo, Yin Yiqing, et al. Perioperative plasma neuron-specific enolase in patients undergoing coronary artery bypass grafting.
Relationship between chemokine concentration and postoperative cognitive function. Basic Medicine and Clinic, 2005,25 (7): 934-935.
8. Guo Xiangyang, Duan He, Wang Jingjie, et al. Blood saving effect and coagulation function of using blood recovery machine during operation
The influence of. Journal of China Academy of Medical Sciences, 26,2004 (2):188-191.
9. Guo Xiangyang, Luo, Duan He, et al. Clinical observation on the application of blood recovery machine in tumor resection. China
Medical Journal 2004,84 (2):107-110.
10. Guo Xiangyang, Luo, Huang Yuguang, etc. Cost-benefit analysis of blood saving effect by using blood recovery machine during operation
Analysis. China Journal of Blood Transfusion, 2004,17 (2):100-1.
1 1. Guo Xiangyang, Luo, Yin Yiqing, et al. Circadian secretion rhythm of melatonin in patients undergoing coronary artery bypass grafting.
Relationship with neuropsychological state. China Anesthesiology, 2004,24 (6): 405-409.
12. Clinical features and perioperative period of multiple endocrine adenomas containing pheochromocytoma.
Management of anesthesia during operation. China Journal of Anesthesiology, 2003,23 (2):10/-104.
13. Guo Xiangyang, Xu, Zhi, et al. Application of hydroxyethyl starch solution in organ reduction surgery for ovarian cancer
Effects of oxygenation. Chinese Journal of Medicine, 2003,83 (2):114-117.
Guo Xiangyang, Li Yong, Ye Tiehu, et al. Application of tetracaine hydrochloride powder in epidural analgesia after thoracotomy.
Basic Medicine and Clinic, 2003,23 (4): 436-439.
15. Guo Xiangyang, Luo, Zhi, etc. Perioperative melatonin secretion rhythm in patients undergoing coronary artery bypass grafting.
Journal of China Academy of Medical Sciences, 2003,25 (5): 445-458.
16. Guo Xiangyang, Li Yong, Ye Tiehu, et al. Clinical study on patient-controlled epidural anesthesia
Analgesia with tetracaine hydrochloride after lobectomy. TMC (Traditional Chinese Medicine)
Science Journal, 2003, 18( 1):54 -58.
17. Guo Xiangyang, Luo. Preoperative evaluation and preparation for pheochromocytoma resection. Journal of practical medicine,
2004,20(5):469-472.
18. Guo Xiangyang, Luo. A new generation of plasma substitute-medium molecular weight hydroxyethyl starch (Hess). China medicine.
Academic Tribune, February 20, 2003.
19. Guo Xiangyang, Luo,, etc.
China Journal of Anesthesiology, 2003,23 (5): 394.
20. Guo Xiangyang, Luo, Huang Yuguang, et al. Clinical characteristics and perioperative anesthetic management of pheochromocytoma.
China Journal of Medicine 2002,82: 523-526.
2 1. Guo Xiangyang, Luo, and so on. Management of perioperative anesthesia in pheochromocytoma complicated with catecholamine heart disease.
Journal of China Academy of Medical Sciences, 2002,24 (4): 422-426.
22. Guo Xiangyang, Luo, Zhi, et al. Multiple endocrine tumors secreting VIP and CCK.
Anesthesia for liver metastases. China Journal of Anesthesiology, 2002,22 (7): 440.
23. Guo Xiangyang, Luo Zhi, et al. Large-capacity lung lavage with double-lumen tracheal intubation under general anesthesia.
Treatment of pulmonary alveolar proteinosis. China Journal of Anesthesiology, 2002,22 (7): 392.
24. Guo Xiangyang, Luo, and others. Pheochromocytoma crisis complicated with tumor rupture and bleeding.
Rescue and experience of a case of shock. China Journal of Medicine 2002,82: 428-429.
25. Guo Xiangyang, Luo, Zhi, et al. Surgical anesthesia for 2 cases of complicated pheochromocytoma. China Journal of Anesthesiology.
Annual Report, 2002,22:167.
26. Guo Xiangyang and Luo. Malignant high fever. Chinese Journal of Anesthesiology, 200 1, 2 1:604-606.
27. Guo Xiangyang, Luo, Ren Hongzhi, et al. Retrospective study on dislocation of arytenoid cartilage after tracheal intubation. China Journal of Medical Science, 1998,13 (2):119-122.
28. Guo Xiangyang, Ye Tiehu, Sang Nuoer, et al. Study on the application of inhalation anesthetics such as desflurane in balanced anesthesia. China Journal of Anesthesiology, 1998, (18):325-327.
29. Guo Xiangyang, Huang Yuguang, Jin, et al. Clinical study on patient-controlled analgesia with subcutaneous and intravenous morphine? Journal of Clinical Anesthesiology, 1999, 15(2):78-79.
30. Guo Xiangyang, Luo Zhi, Zhi et al. jointly applied monitoring indicators such as end-expiratory CO2 and anesthesia management. Journal of China Academy of Medical Sciences,1998,20 (10): 76-79.
3 1. Guo Xiangyang, Luo, Zhi, etc. Application of rigid bronchoscope in airway management after lobectomy. Journal of China Academy of Medical Sciences, 1997, 19(4):293-296.
32. Guo Xiangyang, Luo, Zhi, et al. 5 cases of arytenoid cartilage dislocation after tracheal intubation. China Journal of Anesthesiology, 1997, (17):697-698.
33. Guo Xiangyang, Xu Shouchun, Luo, etc. Effect of captopril on metabolism of high energy phosphate in myocardial tissue. Chinese Journal of Thoracic Cardiovascular Surgery, 1998,14 (2):115-17.
34. Guo Xiangyang, Luo, Xu Shouchun, etc. Protective effect of captopril on myocardial ischemia-reperfusion and its mechanism. Journal of China Academy of Medical Sciences,1998,20 (3): 220-225.
35. Guo Xiangyang, Luo, Xu Shouchun, etc. Effects of captopril on hemodynamics after myocardial ischemia-reperfusion in dogs. Journal of China Academy of Medical Sciences, 1997,19 (3): 21216.
36. Guo Xiangyang, Luo, Xu Shouchun. Effect of captopril on ultrastructure of ischemia-reperfusion injury in dogs. Chinese Journal of Medicine,1996,76 (10): 733-737.
37. Guo Xiangyang, Luo, Ye Tiehu, etc. Prevention of postoperative nausea and vomiting with sufuning. Chinese Journal of Surgery.1994,32 (7): 435-437.
38. Guo Xiangyang, Luo Laikui, Luo, etc. Application and effect analysis of different administration methods of Wankesong in rapid tracheal intubation. Chinese Journal of Anesthesiology. 1995, 15 (2): 66-68.
Guo Xiangyang, Yu Ruiying, Luo, et al. Epidural application of cervical segment. Journal of China Academy of Medical Sciences, 1993, 15(6):437-440.
40. Guo Xiangyang and Yu Ruiying. Cause analysis of nerve root injury caused by cervical epidural block. China Journal of Anesthesiology, 1993, 13(7):452.
4 1. Guo Xiangyang summarized and Luo revised. Progress in clinical pharmacology of intravenous anesthesia. &; Laquo foreign medicine &; Raquo anesthesia and resuscitation
Su fascicle, 1998,19 (4):193-196.
42. General introduction of Guo Xiangyang, revised by Luo Xushouchun. Microvascular stunning and vascular endothelial cell protection. &; Laquo foreign medicine &; Raquo Anesthesia and Resuscitation Volume, 1997, 18 (6): 32 1-323.
43. Guo Xiangyang summarized, Luo and Xu Shouchun summarized the research progress of captopril on myocardial ischemia-reperfusion injury. &; Laquo foreign medicine &; Raquo Anesthesia and Resuscitation Volume, 1998, 19(2):68-70.