1. Sterilized and sterile preparations are not included.
A. Injection B. Implantation
C. Rinse D. Spray
E. ointment for injuries and burns.
2. Glucose injection belongs to the type of injection is
A. sterile powder for injection
B. sol injection
C. suspension injection
D. emulsion perfusion method
E. solution injection
3. Water-insoluble drugs or solid drugs that need to be prolonged after injection can be made into injections.
A. sterile powder for injection
B. solution injection
C. suspension injection
D. emulsion perfusion method
E. sol injection
4. For drugs that are easily soluble in water and unstable in aqueous solution, the types that can be made into injections are
A. sterile powder for injection
B. solution injection
C. suspension injection
D. emulsion perfusion method
E. sol injection
5. The description of injection characteristics is wrong.
A. the curative effect is rapid and reliable.
B. suitable for drugs that are not suitable for oral administration.
C. it is suitable for patients who cannot take drugs orally.
D. it can produce local positioning effect.
E. Easy to use
6. The pH value of general injection should be
A.3~8B.3~ 10
C.4~9D.5~ 10
E.4~ 1 1
7. The water for injection specified in China Pharmacopoeia should be
A. pyrogen-free distilled water
B. distilled water
C. Sterile distilled water
D. deionized water
E. water prepared by reverse osmosis
8. The wrong statement about commonly used pharmaceutical water is
Purified water is pharmaceutical water prepared from raw water by distillation, ion exchange, reverse osmosis and other suitable methods.
B. Pure water does not contain any additives.
C. The water for injection is distilled water in purified water.
D water for injection can be used as a solvent for sterile powder for injection.
E purified water can be used as a solvent for preparing common pharmaceutical preparations.
9. The solvent used to prepare the injection is
A. Pure water B. Water for injection
C. Sterile distilled water D. Sterile water for injection
E. Pharmaceutical water
10. Sterile powder for injection or solvent for diluent for injection
A. Pure water B. Water for injection
C. Sterile distilled water D. Sterile water for injection
E. Pharmaceutical water
1 1. The main differences between water for injection and purified water inspection items are
A.ph.b. pyrogen
C. chloride D. ammonia
E. sulfate
12. Penicillin powder for injection should be added before use.
A. Water for injection B. Sterile distilled water
C. deionized water D. sterile water for injection
E. distilled water
13. The wrong statement about pyrogen is
A. pyrogen is a metabolite of microorganisms.
B.what is the strongest heating capacity? Blue positive bacilli institute
Pyrogen produced
C. fungi can also produce pyrogens.
D. activated carbon has strong adsorption to heat.
E. pyrogen is endotoxin produced by microorganisms.
14. The ones with particularly strong pyrogen activity are
A. ribonucleic acid B. cholesterol
C. lipopolysaccharide d protein
E. phospholipids
15. The narrative error about the nature of pyrogen is
A.it will be destroyed by high temperature.
B.it is water-soluble.
C. volatility
D. it can be destroyed by strong acid and alkali.
E. easy to be adsorbed
16. pyrogen removal method does not include
A. High temperature method B. Acid-base method
C. adsorption method D. microporous membrane filtration method
E. ion exchange method
17. Needles for injection or other glassware can be used to remove pyrogen.
A. High temperature method B. Acid-base method
C. adsorption method D. microporous membrane filtration method
E. ion exchange method
18. pyrogen can be removed when preparing injection.
A. High temperature method B. Acid-base method
C. adsorption method D. microporous membrane filtration method
E. ion exchange method
19. The statement about the nature of pyrogen is wrong.
A. it has heat resistance.
B.it is filterable.
C. water-soluble
D. non-volatile
E. having the property of being oxidized.
20. Can't remove pyrogen method is
A. High temperature method B. Acid-base method
C. freeze-drying method D. adsorption method
E. reverse osmosis method
2 1. The statement about the route of pyrogen pollution is wrong.
A. introducing from water for injection
B. Bring it in from raw and auxiliary materials
C. from containers, pipelines and equipment.
D. Drug decomposition and production
E. pollution in that preparation proces
22. The misrepresentation about pyrogen heat resistance is
Heating at 60℃ for 65438 0 hours will not affect pyrogen.
B heating at l00℃ will not cause pyrolysis of pyrogen.
C heating at 180℃ for 3 ~ 4 hours can completely destroy the pyrogen.
D heating at 250℃ for 30 ~ 45 minutes can completely destroy pyrogen.
Heating at e 400℃ for 65438 0 minutes can completely destroy the pyrogen.
23. The misrepresentation about pyrogen is
Pyrogen is a general term for trace substances that can cause abnormal temperature rise in warm-blooded animals.
B. Most bacteria can produce pyrogens. What is the strongest heating capacity? Pyrogen produced by blue-negative bacilli
C pyrogen is endotoxin produced by microorganisms and exists between the cell membrane and solid membrane of bacteria.
Endotoxin is a complex composed of phospholipids, lipopolysaccharide and protein.
E. protein is the heating center of endotoxin.
24. The antioxidant that should be added when preparing the easily oxidizable drug injection is
A. Sodium bicarbonate B. Sodium metabisulfite
C. sodium chloride ethylenediamine tetraacetate
E. sodium citrate
25. The isotonic regulator that should be added in the injection preparation is
A. Sodium bicarbonate B. Sodium chloride
C. Sodium metabisulfite and sodium citrate
E. disodium edetate
26. The metal ion chelating agent that should be added when preparing the easily oxidizable drug injection is
A. Sodium bicarbonate B. Sodium chloride
C. Sodium metabisulfite and sodium citrate
E. disodium edetate
27. The following methods can not increase the solubility of drugs are
A. adding cosolvent
B, adding nonionic surfactant
C. making salt
D. Application of latent solvents
E. adding suspending agent
28. The polarity of the solvent directly affects the drug.
A.b. stability
C. Wettability D. Dissolution rate
E. water retention
29. The correct statement about solubility is
Solubility refers to the maximum amount of drug dissolved in a certain amount of solvent under a certain pressure.
B solubility refers to the maximum amount of drug dissolved in a certain amount of solvent at a certain temperature.
C solubility refers to the amount of drug dissolved in water at a certain temperature.
D solubility refers to the amount of drug dissolved in solvent at a certain temperature.
E solubility refers to the amount of drug dissolved in a solvent under a certain pressure.
30. The factors affecting the solubility of drugs do not include
A. Drug polarity B. Solvent
C. Temperature D. Color of medicine
E. crystalline forms of drugs
3 1. When preparing the drug solution, in order to increase the drug, heat and stir the solvent.
A.b. stability
C. Wettability D. Dissolution rate
E. water retention
32. In the presence of sodium benzoate, the solubility of caffeine increases from 1: 50 to 1: 1, because
A. Dissolution B. Anticorrosion
C. emulsification D. suspension additives
E. dissolution
33. Phenobarbital has the largest solubility in 90% ethanol solution, which is
A. cosolvent B. solubilizer
C. Disinfectant D. Polar solvent
E. cosolvent
34. When preparing insoluble drug solution, the role of adding Tween is
A. cosolvent B. solubilizer
C. emulsifier D. dispersant
E. cosolvent
35. In order to prepare a 5% aqueous iodine solution, the usual methods are as follows.
A. Making salt B. Making ester
C. adding solubilizer D. adding cosolvent.
E, adopting a composite solvent.
36. The statement about the characteristics of injections is wrong.
A. Rapid drug action B. Accurate dose
C. Easy to use D. Reliable function
E. it is suitable for drugs that are not suitable for oral administration.
37. The following routes of administration, an injection amount should be below 0.2ml for
A. Intravenous injection B. Intraspinal injection
C. intramuscular injection D. intradermal injection
E. subcutaneous injection
38. The advantages of injection include
A. it has fast onset, accurate dosage and reliable action.
B. it is suitable for patients who can't take drugs orally.
C. suitable for drugs that are not suitable for oral administration.
D. the drug action can be quickly terminated.
E. it can produce directional effect.
39. The quality requirements of injections do not include
A. Infertility
B. pyrogen-free
C. pale
Osmotic pressure is equal to or close to plasma osmotic pressure.
E. the ph value is equal to or close to blood.
40. It can only be administered by intramuscular injection, right?
A. low molecular weight solution injection
B. Injection of polymer solution
C. emulsion perfusion method
D. suspension injection
E. freeze-dried powder for injection
4 1. The emulsifier that can be used for intravenous fat emulsion is
A. Arabic gum
B. tragacanth
C. soybean phospholipids
D. fatty acid sorbitol
E. sodium dodecyl sulfate
42. The route of administration without absorption process is
A. intravenous injection B. intraperitoneal injection
C. intramuscular injection D. oral administration
E. pulmonary administration
43. The statement about pure water is wrong.
A. It can be used as an extraction solvent for decoction pieces used in the preparation of traditional Chinese medicine injections.
B, it can be used as an extraction solvent for decoction pieces used in the preparation of traditional Chinese medicine eye drops.
C it can be used as a solvent for preparing oral preparations.
D, it can be used as a solvent for preparing external preparations.
E it can be used as a solvent for preparing injections.
44. Vitamin C injection prescription, can't add accessories are
A. disodium edetate b sodium bicarbonate
C. Sodium bisulfite-hydroxyphenyl ethyl ester
E. Water for injection
45. When preparing VC injection, gas should be introduced to drive oxygen, and the best gas is
A. Hydrogen B. Nitrogen
C. Carbon dioxide D. Ethylene oxide
E. chlorine gas
46. The incorrect statement of vitamin C injection is
A. sodium bisulfite can be used as an antioxidant.
B, add sodium bicarbonate to the prescription, adjust the pH to alkaline, and avoid pain during intramuscular injection.
C. disodium EDTA can be used to complex metal ions to increase the stability of vitamin C.
D water for injection used in preparation should be saturated with carbon dioxide.
E. sterilize with 100℃ circulating steam for 65438 05 minutes.
47. The account of infusion is incorrect.
A. bacteriostatic agents shall not be added in infusion.
B special attention should be paid to sterility, pyrogen-free and clarity during infusion.
C. osmotic pressure can be isotonic or hypotonic.
D. filtration of infusion, fine filtration at present, microporous membrane is mostly used.
E. the pH value of infusion is in the range of 4 ~ 9.
48. The account of infusion is incorrect.
A. Infusion refers to injecting a large dose of injection into the body through intravenous drip.
B. There must be no pyrogen except sterility.
Osmotic pressure should be isotonic or hypertonic.
D. in order to ensure sterility, bacteriostatic agents should be added.
E. the clarity shall meet the requirements.
49. The narrative error about plasma substitutes is
A. plasma substitutes have the function of replacing whole blood in the body.
Plasma substitutes should not interfere with blood group tests.
C. it does not interfere with the oxygen-carrying function of red blood cells.
D in the blood circulation system, it can be kept for a long time and is easily absorbed by the human body.
E. do not accumulate in organs and tissues.
50. Which preparation method is suitable for preparing injections for drugs that are sensitive to heat and unstable in aqueous solution?
A, adopting a sterilization solvent crystallization method to prepare sterile subpackaged products for injection
B. freeze-dried products for injection.
C, preparing sterile subpackaged products for injection by spray drying.
D. injection prepared by aseptic operation.
E. injection prepared by low-temperature sterilization.
The quality requirements of 5 1. eye drops are different from those of injections.
A. It has a certain ph value and is isotonic with tears.
C. Sterility D. Transparency meets the requirements
E. pyrogen-free
52. The statement about eye drops is incorrect.
A. Eye drops are liquid preparations for external use that are directly used in eyes.
B. the tolerance pH value of normal eyes is 5.0 ~ 9.0.