This topic examines the responsibility system for safe production. The purpose of establishing the responsibility system for production safety is: on the one hand, to enhance the sense of responsibility for production safety of the responsible personnel at all levels, functional departments, their staff and personnel in various positions in production and business units; On the other hand, it is to clarify the responsibilities of the responsible personnel at all levels, functional departments and their staff and personnel at all positions in production and business units, so as to fully mobilize the enthusiasm and subjective initiative of personnel at all levels and departments in safety production and ensure safety production. The significance of establishing the responsibility system for production safety is mainly reflected in two aspects: first, to implement China's production safety policy and the specific requirements of relevant laws and policies on production safety; Second, by clarifying the responsibilities, all kinds of personnel really attach importance to the work of safety in production, which plays an important role in preventing accidents, reducing losses, investigating and handling accidents and building a harmonious society.