Hefei No.45 Middle School is a junior high school affiliated to Luyang District of Hefei City, which was built at 1937. At present, it is four districts and one school. The school has nearly 400 teachers and more than 6,000 students. Hefei No.45 Middle School is the first batch of characteristic junior high schools in Hefei, the first batch of quality education demonstration schools, a civilized unit in Anhui Province and an advanced collective in the national education system.

The school has long adhered to the dual-track development (students' academic level and comprehensive quality) and trained a large number of outstanding junior high school graduates with both ability and political integrity. Since the admission rate of 1985, the school has trained 15 champions of Hefei senior high school entrance examination, which has been praised as "the cradle of champions of senior high school entrance examination" by the society. The school's "Sailing" Science and Technology Society has successively trained 16 winners of the Mayor Award for Youth Science and Technology Innovation in Hefei;

Hefei No.45 Middle School is a traditional chess school in Anhui Province. China has made outstanding achievements in chess and Go, and won the team championship of Anhui Youth Chess Championship for many times. The "Turing" information society won the olympiad in informatics 10 consecutive championship for Hefei teenagers; The Cuckoo Choir won the world choir games Silver Award.