Nobel Prize in Physiology or Medicine. After Tu Youyou, according to the standard of Nobel Prize, Zhang Tingdong's arsenic therapy for leukemia, Wang Xuechang's arc-edged acupuncture for neck, shoulder, waist and leg pain, Sheng Zhiyong's burn course and new therapy, the splicing structure and mechanism of history and the principle of acupuncture analgesia may all win the Nobel Prize in physiology or medicine.

Here is a brief introduction to a few people:

Zhang Tingdong: Arsenic Therapy for Leukemia

Zhang Tingdong, 1932 1 1 was born in wuqiao county, Hebei Province in June. He graduated from Harbin Medical University and is the director and professor of Chinese medicine in the First Affiliated Hospital of Harbin Medical University. Focusing on hematological diseases, we undertake the mechanism study of integrated traditional Chinese and western medicine treatment and curative effect of leukemia. Published 65,438+002 academic papers and 3 monographs, and discussed the treatment of M3 leukemia, with the disease number 1.

Professor Zhang Tingdong's most important contribution is his innovative research on arsenic (arsenic trioxide) therapy for leukemia.

The chemical composition of arsenic is arsenic trioxide. Treating diseases with arsenic, fighting poison with poison, Chinese medicine has a long tradition, which has been used in the west. The medicinal properties of arsenic were recorded in Kaibao Materia Medica in the Northern Song Dynasty and Compendium of Materia Medica by Li Shizhen in the Ming Dynasty. Arsenic trioxide was also used to treat leukemia in the west in the19th century and 1930s, but it was not generally accepted.

Wang Xuechang: Treating Neck, Shoulder, Lumbago and Leg Pain with Arc Blade Acupuncture

Wang Xuechang, director of pain department of Henan Provincial Hospital of Traditional Chinese Medicine (Second Affiliated Hospital of Henan College of Traditional Chinese Medicine), leader of neck, shoulder, back and leg pain and acupotomy, inventor of "multifunctional buried needle" and arc-edged acupotomy, proposer of "five principles of treating neck, shoulder, back and leg pain", lecturer of national continuing education program of traditional Chinese medicine, lecturer of "eight in one" elite training class of neck, shoulder, back and leg pain in Wang Quanguo, 65438+.

Wang Xuechang's main contribution is to develop the arc-edged acupuncture method which has obvious curative effect on neck, shoulder, back and leg pain.

At present, the disease of neck, shoulder, back and leg pain is not only one of the most common frequently-occurring and chronic diseases in China, but also one of the most common diseases in the world. It is even called the second largest "epidemic disease" in the world, which puzzles people all over the world. As the innovation and development of ancient acupuncture and moxibustion medicine in China, arc-blade acupuncture has been clinically proved to have magical curative effect, which is undoubtedly another important contribution of China medicine to the human world.

Sheng Zhiyong: the law of burn course and new treatment

Sheng Zhiyong, trauma surgeon, burn expert, academician of China Academy of Engineering, one of the pioneers of China Burn College.

1942 graduated from Shanghai medical college. Leader of the Expert Group of Clinical Department of 304 General Hospital of PLA, honorary director of the Institute of Burn Research of the whole army, professor and doctoral supervisor of Nankai University School of Medicine. He has been a member of the Chinese Medical Association, chairman of the China Society of Burn Surgery, member of the Standing Committee of the China Society of Traumatic Surgery and member of the Medical Science and Technology Committee of the People's Liberation Army.

At an international burn conference in 1990, Sheng Zhiyong's students filmed a documentary recording the treatment process of Sun Bo (95% of the total burn area and 90% of the deep burn area) and showed it. Immediately, the venue caused a shock. After watching the video introduction, a foreign professor was so excited that his eyes filled with tears that he picked up the China expert introduced at the scene and turned around twice.

In the treatment of burns, Sheng Zhiyong advocated using whole blood resuscitation, hemodynamic monitoring to guide infusion volume, CO2 tensiometer monitoring and anisodamine to improve intestinal blood supply, and affirmed the importance of oxygen free radical damage and prevention after burns. After shock, extensive escharectomy made the clinical cure rate of burns reach 99.6%, and LA50 reached 98% (third degree LA50%86%).

Guide the research and application of cryopreserved skin; To study the translocation of intestinal bacteria and endotoxin after trauma and burn, and to provide theoretical basis for the prevention and treatment of infection and sepsis after trauma and burn. During the Seventh Five-Year Plan, the Eighth Five-Year Plan, the Ninth Five-Year Plan and the Tenth Five-Year Plan, he led the research and prevention of post-traumatic multiple organ failure (MSOF) in the PLA.

Sheng Zhiyong said in an interview that he is studying the worldwide problem of sweat gland reconstruction after skin grafting. "We have successfully transplanted skin in a small area, but it will take some time for a large area of sweat gland reconstruction research. I hope I can have no regrets at the moment I close my eyes. "

Extended data:

The Nobel Prize in Physiology or Medicine was established according to the will of the late Swedish chemist alfred nobel, aiming at commending those who made outstanding discoveries in physiology or medicine in the previous year.

The front of the Nobel Prize in Physiology or Medicine is a bust of Nobel, the right side is the year of Nobel's birth and death (Roman numerals), and the author's signature in the lower left corner is "E.LINDBERG 1902".

The design on the back of the medal is Xu Guiya, the goddess of health in ancient Greek mythology, who is collecting spring water on the rock to quench the thirst of sick girls. The medal is engraved with a Latin sentence, which roughly translates as: New discoveries make life better.

190 1 The first prize was awarded by karolinska institutet of Stockholm Medical University, Sweden. The award ceremony was held on 12, the anniversary of Nobel's death.