1. laxative effect: all kinds of aloe plants contain anthraquinone derivatives, especially aloe-emodin; These anthracene-containing glycoconjugates must release emodin in the intestine to play a stimulating purgative role. Among all rhein laxatives, aloe is the most irritating, with obvious abdominal pain and pelvic congestion, which can cause nephritis in severe cases. Due to the different contents of active ingredients in various aloe, it is suggested that pure aloe-emodin should be used instead of aloe as a laxative. Dogs (2-5g) and cats (0.2- 1.0g) can cause diarrhea. It has no promoting effect on peristalsis of isolated small intestine; Diarrhea mainly affects the large intestine. A suspension of Aloe Vera var. heterophylla (400 mg/ml) produced in Yunan, China was given to male rats, and its purgative effect was similar to that of imported Aloe Vera. In addition, injecting aloe extract into dogs can increase the secretion of small intestinal fluid and the activity of lipase, and sometimes it can also increase the activity of dipeptidase. Too high a dose will inhibit it.
2. Protective effect on experimental liver injury:
2. Protective effect of1.on carbon tetrachloride-induced liver injury: mice were intraperitoneally injected with aloe extract, total glycosides of 225mg/kg×4d, Crystal III10ml/kg× 4d or total glycosides of 200mg/kg×3d, and 0. 1%CCl4 paraffin oil/kloc-could be injected.
2.2. It can also reduce the increase of SGPT induced by thioacetamide in mice, and its activity is close to 200 mg/kg× 3d biphenyl diester.
2.3. It can also reduce the increase of SGPT in rats caused by galactosamine. Compared with the control group, aloe injection 10 ml/kg× 4d P.