Mainly using PCR amplification, gene sequence analysis, gel electrophoresis, spectroscopy, television micro-electrophoresis, liquid chromatography-mass spectrometry and other means to engage in the interaction between small molecules and protein, nucleic acid and macromolecular structure, function, environmental pollution and health research. 38 papers were published, including 25 papers by the first author SCI, and the impact factor of a single paper was 9.624. Published papers are covered by cells; ; Account. Chemistry. Resmore Cell & protein omics and other internationally renowned publications have been cited for more than 200 times.