Human diseases are closely related to genes. With the development of medicine, leukemia, thalassemia, renal failure and so on. Can be detected by the latest genetic technology, and then find a suitable donor for transplantation.
HLA*** can be divided into four types: Type I molecules, including HLA-A, HLA-B and HLA-C, are widely found in various tissues and cells;
Type II molecules, including HLA-DP, HLA-DQ and HLA-DR, exist in B cells, macrophages and activated T cells.
Type III molecule is a complement system, including C2 and C4 sites, which exists in serum.
Type ⅳ molecules may be some differentiation antigens, which only exist in lymphocytes, some cytotoxic T cells and white blood cells.