It is understood that 464 teams from the whole province participated in the fierce competition. Finally, The Mechanism of Abnormal Splicing of DVL2 Caused by SF3B 1 K700E Mutation, written by the representative team of China-Japan Friendship Hospital of Jilin University, stood out and won the first prize of Jilin Province, and was shortlisted for the national finals. The representative team of China-Japan Friendship Hospital of Jilin University will be the only team in Jilin University to compete for the national competition award.
As one of the top 57 national college students' life science competitions recognized by the Ministry of Education, it is an extracurricular academic science activity competition for college students established by the National College Students' Life Science Competition Committee under the initiative and guidance of the College Biology Curriculum Teaching Steering Committee and the College Biology Professional Teaching Steering Committee of the Ministry of Education, the joint meeting of the College Biotechnology and Bioengineering Professional Teaching Steering Committee of the Ministry of Education, the National College Experimental Teaching Demonstration Center, and the magazine "College Biology Teaching Research" (electronic version).
The research of the team of China-Japan Friendship Hospital of Jilin University is a supplement and perfection to the existing RNA splicing theory, and clarifies the mechanism that the mutation of SF3B 1 leads to the abnormal splicing of the important cancer gene DVL2, which lays a foundation for cancer treatment targeting the mutation of SF3B 1.
This project is directed by Professor Wan Zhenxin and Professor Hu Xin, director of the Tumor Biology Laboratory of Jilin University. The team consists of five members from Sino-Japanese Friendship Hospital of Jilin University, Tang Aoqing Science Experimental Class, First Hospital of Jilin University and School of Life Sciences. The whole competition was completed in the Tumor Biology Laboratory of China-Japan Friendship Hospital of Jilin University. Team members adopt a combination of online and offline methods, actively explore and study, and gradually improve the experimental scheme. Under the careful carving and polishing of the team members and teachers, we finally achieved excellent results.