There are no diagnostic criteria for advanced breast cancer and metastatic breast cancer. The following is the definition of breast cancer recurrence. You can look at the Breast Surgery edited by Guo, which describes it like this:

Tumor recurrence means that the tumor has disappeared after treatment, and after a certain period of time, the same tumor reappears. The so-called tumor has disappeared, which refers to the range that can be identified by naked eyes or clinical examination. From the pathological point of view, the recurrence of tumor must be the residual cancer cells somewhere in the body. Japan's Breast Cancer Management Agreement defines that breast cancer recurs after treatment (surgery, radiotherapy, chemotherapy, etc.). ) determined by histology is called recurrence, but many cancers need to be excluded. Guo Breast Surgery divides the recurrence of breast cancer into local recurrence and metastatic recurrence. You can look at the details again.