Immunoglobulin E(IgE) refers to an antibody of human body, which exists in blood. It is the lowest IgE content in normal human serum and can cause type I hypersensitivity. And people with excessive IgE are called "allergic constitution". \ x0d \ x0d \ allergic constitution (allergic constitution) generally refers to people who are prone to allergic reactions and allergic diseases and can't find the cause, which is called allergic constitution "allergic constitution". People with "allergic constitution" can have various allergic reactions and allergic diseases, such as eczema, urticaria and allergic asthma, and some of them are particularly sensitive to certain drugs, which can lead to drug dermatitis and even exfoliative dermatitis. \ x0d \ x0d \ People with "allergic constitution" often have the following characteristics: \x0d\① Immunoglobulin E(IgE) is an antibody that mediates allergic reaction, and the serum IgE content of normal people is very low, while the serum IgE of some people with "allergic constitution" is higher than that of normal people1.000-10.0000. \x0d\② There are a certain proportion of helper T cells 1(Th 1) and helper T cells 2(Th2) in normal people, which coordinate with each other to maintain human immune balance. Some people with "allergic constitution" are often dominated by Th2 cells. Th2 cells can secrete a substance called interleukin -4(IL-4), which can induce the synthesis of IgE and increase the serum IgE level. \ x0d \ x0d \ antiallergic probiotics can participate in IgE-mediated immune allergic reaction. After human dendritic cells are co-cultured with antiallergic probiotics, the immune function of Th 1 which regulates the secretion of interleukin (IL- 12) can be used to screen antiallergic lactic acid bacteria strains with antiallergic ability. Fuminkang probiotics improve the ecological balance of intestinal microorganisms, the largest immune organ of human body, by using active and non-pathogenic microorganisms, thus promoting the immune tolerance function. International patent certification of Lactobacillus salivarius containing antibody for reducing serum IgE allergy. After continuous supplementation for more than three months, the concentration of IgE in the body was reduced, so that allergens could not combine with IgE antibodies in the body, and a series of allergic biochemical reactions no longer occurred.