Data show that with the improvement of people's living standards and the change of diet structure, the incidence of colon cancer is increasing year by year. Colon cancer is a serious disease that harms human health and poses a great threat to human physical and mental health. Once diagnosed, it must be treated in time. So what is the metastasis of colon cancer? 1, organ metastasis The distant metastasis of colon cancer is mainly the liver, and about 50% patients will have liver metastasis before or after operation. The data also showed that about 30% patients had occult liver metastasis that could not be found by preoperative B-ultrasound or CT. Resection of liver metastasis from colorectal cancer is safe and may improve the long-term survival rate of patients with metastasis. But only a small part (10%-20%) was suitable for surgical resection, and 70% of them recurred after operation. 2. Lymphatic metastasis of colon cancer generally spreads from near to far in the following order, but there are also disorderly spanning metastasis. (1) The colonic lymph nodes are located on the fat side of the intestinal wall. (2) Paracolonic lymph nodes are located in the mesentery adjacent to the colon wall. (3) Mesangial vascular lymph nodes are located beside the blood vessels in the middle of the mesocolon, also called intermediate lymph nodes. (4) Mesangial root lymph nodes are located at the mesenteric root. After cancer invades the muscle layer of intestinal wall, the possibility of lymphatic metastasis increases. If the subserous lymphatic vessels are invaded, the probability of lymphatic metastasis is greater. 3, blood transfer Under normal circumstances, cancer cells or tumor thrombi first reach the liver along the portal vein system, and then transfer to other tissues and organs such as lungs, brains and bones. Hematogenous metastasis is usually caused by cancer invading capillaries and venules, but it can also be caused by pressing the tumor during physical examination, squeezing the tumor during operation, and even strong peristalsis during obstruction. 4. Invasion of implant cancer can directly invade surrounding tissues and organs. Cancer cells shed in the intestinal cavity, which can be planted on mucous membranes elsewhere, shed in the abdominal cavity, or planted on the peritoneum. Metastasis is nodular or millet-shaped, white or grayish white and hard. Spreading to the whole abdominal cavity can cause cancerous peritonitis and ascites. The above is the knowledge of colon cancer metastasis.