Mainly engaged in the research on the function and evolution of immune genes and molecules of various species in different evolutionary States. Since returning to China 16 years ago, he has focused on the frontier field of the origin and evolution of vertebrate immune system and achieved many major original and systematic achievements. * * * has obtained 42 invention patents in China and 1 in the United States; The correspondent has published SCI papers 138, including 5 IF≧ 10 papers, such as genomes, Am J Hum Genet5 & lt if< 10 papers 14, such as: J Immunol, J Biol Chem, Cell Res, etc. Discovery of Exogenous Apoptosis Signal Pathway of Chordata Animals was published in Science Signal along with the cover paper, and was selected as one of the "Top Ten Scientific and Technological Progress of Universities in China" in 20 10. The published articles have been cited by Nature, Nat Rev Immunol, Nat Rev Genet, Nat Rev Microbio, Nat Rev Drug Discov, Immunol Rev, PNAS, Curr Opi Microbio, Curr Opi Immunol, Genome Res, Curr Biol, etc. IF is more than 10 times. The magazines Nature and Science Signal mainly reported two articles. Professor Xu has co-published papers in New England Medicine, Nature and PNAS. In the research related to traditional Chinese medicine, the author's papers are published in the following journals: Planta Med, currmed chem, jaltern complement med, j med chem, bioorg med chem, Euro j med chem, biochem pharmacol. He published articles and was cited more than 1000 times.