Ultrasound can only find fetal structural abnormalities, but at the moment of sperm-egg combination, chromosome pairing will inevitably go wrong, resulting in fetal chromosome or gene abnormalities, but usually ultrasound takes four to five months to find abnormalities. Early chromosome examination depends on amniocentesis, and the advent of noninvasive fetal chromosome gene detection (NIFTY PLUS) greatly advanced the fetal chromosome examination to 10~ 12 weeks, with high accuracy and high value for prenatal examination.
Early chromosome screening can greatly reduce anxiety during pregnancy. Dr. Li said that amniocentesis should wait until 16~ 18 weeks. Although amniocentesis is a mature technique, according to research, there is still the risk of 1~3/ 1000 abortion or stillbirth. Noninvasive fetal chromosome gene detection (NIFTY PLUS) can be performed after the first pregnancy 10 weeks. Compared with amniocentesis (16~ 18 weeks), the fetus can be known six weeks in advance, which greatly reduces the anxiety of pregnant women. If the baby's chromosome abnormality is found in case, it will help the doctor to take appropriate medical measures as soon as possible. At present, non-invasive fetal chromosome gene detection has been listed as a first-line prenatal screening project in the world because of its high accuracy (> 99%), and low-risk pregnant women do not need amniocentesis.
Prenatal examination needs to know which items meet the screening benefits. At present, there are 20 items that can be checked by noninvasive fetal chromosome gene detection (NIFTY PLUS). In addition to the basic Down's disease, Edward's disease, Bartonella disease and sex chromosome abnormality, there are also 10 common chromosome fragment deletion diseases (the incidence is about110000) which are also screened. For example: chubby Willis syndrome, angel syndrome, cat crying syndrome, Degeorge's disease II, hereditary cleft lip and palate (rabbit lip), Jacobson syndrome, 1p36 deletion syndrome, 2q33. 1 deletion syndrome, 16p 12 deletion. In addition to the above common chromosome abnormality/deletion diseases, the incidence of many chromosome microdeletions is even lower than one in 200,000. At present, it is still in the stage of continuous research and needs more clinical verification and accumulation. It is expected that there will be more complete testing items in the near future.
Before receiving the examination, you must consult the obstetrician Dr. Li Musheng. Before receiving the examination, be sure to consult an obstetrician to understand the following points:
There is a high correlation between the size of clinical data and the accuracy of detection. The quality of large-scale testing units with large-scale clinical experience is reliable. The testing unit itself has public data verification, which is published in international papers and periodicals, indicating that it can stand the test. The genes of Asians are slightly different from those of Europeans and Americans, so it is better to compare the genes of Asians (China people). At present, 20 non-invasive fetal chromosome gene detection (NIFTY PLUS) needs more than 20,000 yuan at its own expense. Dr. Li hopes that this technology will flourish in the future and benefit pregnant women at the expense of the people. More details: /genehealth/
Subject: nifty, gene, gene detection, obstetrics and gynecology, pregnant women, chromosomes, prenatal examination, amniocentesis, fetus, noninvasive and noninvasive fetal chromosome gene detection