Save Your Knee "Injecting joint lubricant (such as hyaluronic acid) can effectively control knee joint degeneration? In recent years, it is also very popular to inject hyaluronic acid (hyal- original meaning: as bright and transparent as glass) into the joint cavity to treat "degenerative" knee arthritis. Hyaluronic acid is a well known mistranslation. The correct name is hyaluronic acid, which is one of the main components of synovial fluid and cartilage. It has special biological activity, can carry more than 500 times of water, has good water retention, is non-toxic, has low immune response, is highly biocompatible and biodegradable, and can be absorbed by human body. For a long time, it has been widely used in various medical fields, such as promoting wound healing, ophthalmic surgery, surgical adhesion prevention and wrinkle removal in cosmetic medicine. Some are extracted from fresh Celosia cristata and some are synthetic. Hyaluronic acid injected into the knee joint cavity is like lubricating oil for rusty gears. It can cover the surface of cartilage to protect cartilage, increase lubrication and avoid joint contracture, thus enhancing the range of motion of joints, improving the quality of daily life, reducing the continuous wear of cartilage and delaying the time of replacing artificial joints. In recent years, many clinical trials sponsored by drug dealers have affirmed its excellent curative effect, so patients are flocking to it. However, the medical team of the Department of Geriatrics and Immunorheumatology of the University of Copenhagen in Denmark recently published an objective research report in the Scandinavian Journal of Immunorheumatology, which is worthy of reference. Conclusion Intraarticular injection of hyaluronic acid or normal saline has similar effect. The medical team designed a rigorous clinical trial. They randomly divided 25/kloc-0 patients with "degenerative" knee arthritis with similar severity into three groups in a double-blind way, and applied the following different preparations every week, with four doses before and after: group 1: injected with 2 ml of hyaluronic acid; Group 2: 20 ml of normal saline (dilating joint cavity, which can relieve symptoms); The third group: saline 2 ml (control group). After treatment, the patients were observed for 26 weeks. The results showed that there was no statistical difference in pain relief, functional improvement and analgesic use among the groups. In terms of objective pain scale (VAS) and detailed knee joint injury and degenerative arthritis outcome score (KOOS), all three groups have the same degree of improvement, which indirectly proves that intra-articular injection has a similar effect to placebo. Symptom treatment has such a short-term effect, but what about long-term use? Can you slow down or even reverse joint degeneration? Unfortunately, up to now, there is still no credible report! In recent years, the research reports of intra-articular injection have mushroomed, which are full of academic circles and dazzling. Clinicians can also find enough evidence to support whether to carry out intra-articular injection. In September of 20 13, there was an interesting and thought-provoking systematic review paper. Forty-eight systematic review reports on hyaluronic acid injection in the treatment of "degenerative" knee arthritis were reviewed. These studies are prospective, randomized and placebo-controlled clinical trials. According to their conclusion on the therapeutic effect, whether it is related to whether the research is supported by the manufacturer or not, 30 (62.5%) research statements are supported by the manufacturer, only 3 (62.5%) statements are irrelevant to the manufacturer, and 15 (3 1.3%) does not indicate the source of research funds. It was found that all the 30 research results supported by manufacturers supported the curative effect of hyaluronic acid injection, and in addition, 18 did not show conflicts with the interests of manufacturers, and 1 1 thought that the curative effect of hyaluronic acid injection was not better than placebo. Interesting conclusion! After careful inquiry, nine out of ten patients with chronic knee pain who came to our joint center for further treatment received intra-articular injection of hyaluronic acid, and the evaluation was mixed (almost the same as placebo). In view of its high cost, if you can only get short-term placebo effect, you really have to think twice! If it is used improperly (not injected into the joint cavity smoothly) or the joint synovial bursa has allergic inflammatory reaction to hyaluronic acid, it will aggravate the pain, and even the joint synovial bursa will become thicker and lose its elasticity due to repeated inflammation. Occasionally, due to invasive bacterial infection, it is necessary to repeatedly debride and replace the artificial joint early, which is not worth the loss! ▲ Repeated injection of hyaluronic acid leads to bacterial infection, and cartilage is seriously damaged. Only artificial joint replacement surgery can restore function. Excerpt from this article: Your own knee saves a book, more: Degenerative knee arthritis is not degenerative at all in goo.gl/csXHmQ! Are you still drinking glucosamine? Still playing hyaluronic acid? Even expensive platelets? In fact, as long as a new concept, you can make your knees better and better! Attach a simple and easy-to-operate method to maintain the knee joint. Are you still using the wrong concept for the wrong treatment? Twelve misunderstandings about "degenerative knee arthritis": 1. Is a natural aging phenomenon, as long as you are old, it will inevitably happen. 2. Young people will not get degenerative knee arthritis. 3. Once the cartilage of knee joint is destroyed, it cannot be regenerated. 4. Once the knee joint degenerates, it will continue and cannot be stopped or reversed. 5. The incidence of female degenerative knee arthritis is high. 6. Degeneration of knee joint is related to osteoporosis. 7. Glucosamine and chondroitin can effectively control the degeneration of knee joint. 8. Injection of hyaluronic acid can effectively control knee joint degeneration. 9. Platelet concentrated preparation can effectively treat degenerative knee arthritis. 10. Artificial knee replacement is the best method to treat degenerative knee arthritis. 1 1. The smaller the trauma, the smaller the injury and the faster the recovery. 12. Artificial joints can only be used for ten years. Tell you, the above twelve misunderstandings are all wrong! A revolutionary new discovery: degenerative knee arthritis is not degenerative at all! As long as we grasp the golden period of treatment, it is not a dream to restore the health of the knee! Author/Lv Shaorui 1958 was born in Zhudong, Hsinchu-his father, who taught at the Medical College of National Taiwan University at that time, returned to his hometown to become a small-town doctor with the hope of his fellow villagers and elders-so he was born and raised in the hospital, learned his father's medical demeanor from childhood, and embarked on the road of "medical pioneer". Chairman of the knee joint health promotion Committee of Tzu Chi medical volunteers; Director of the International Knee Joint Health Promotion Center of Dalin Tzu Chi Hospital; Director of the Joint Center of Dalin Tzu Chi Hospital; Director of Teaching Department of Dalin Tzu Chi Hospital; Professor of the Ministry of Education; Doctor of Medicine, Yangming University; Doctor of Medicine, Fukuoka University, Japan; Chicago, USA. Yterian-St.Luke Medical Center Researcher, Trauma Center, University of Dubingen, Germany Researcher, Orthopedic Research Fellow, Medical Center, University of Geneva, Switzerland Experienced Vice President of Teaching, Dalin Tzu Chi Hospital Director of Orthopedic Surgery, Chiayi Christian Hospital Director of Arthroscopy and Joint Reconstruction Center, University of Sydney, Australia Visiting Physician of Orthopaedics, University of Bern, Swiss Blog: Stepping Stone-Habitat for Patients with Degenerative Knee Arthritis blog.xuite.net/srlyu/wretch subscribes to Health Aloha Audio-visual Channel, which makes it easier to read health knowledge and join in, and pay attention to your health every day! Line @ ID: @:/beauty/article/32582 Keywords: joint lubricant, hyaluronic acid, degenerative osteoarthritis, aging, osteoporosis, knee joint degeneration.