How did COVID-19 damage the cognitive function of the brain? Sequela of COVID-19 refers to a series of new, recurrent or persistent health problems that may appear within 4 weeks or longer after people are infected with COVID-19 virus for the first time. How does COVID-19 damage the cognitive function of the brain?
How did COVID-19 damage the cognitive function of the brain? 1 10 years1October 26th, according to media reports, a new study conducted by German, French and Spanish scientists found that COVID-19 would kill brain cells called endothelial cells, resulting in cerebral vascular damage, thus impairing cognitive function.
Related papers were published in the recent journal Nature Neuroscience. Previous studies have found that as many as 84% of COVID-19 patients have neurological symptoms, loss of taste or smell, seizures, strokes, loss of consciousness and unconsciousness, which may be one of the reasons.
COVID-19 kills endothelial cells.
Leading to the emergence of "ghost blood vessels"
Although shortly after the COVID-19 outbreak, scientists gradually noticed that COVID-19 infected people had various brain and nerve problems after rehabilitation, but they never found the crux. Now, a new study published in Nature Neuroscience shows that this problem may be solved.
According to reports, this study by German, French and Spanish scientists shows that COVID-19 can not only attack the lungs, but also kill a kind of brain cells called endothelial cells. Endothelial cells are located around the brain and are responsible for protecting the cerebellum and promoting blood flow. The researchers pointed out that the injury of endothelial cells may lead to cerebrovascular injury and cognitive impairment. They said that this discovery may explain why as many as 84% of COVID-19-infected people suffer from "COVID-19 sequelae", such as neurological symptoms, loss of taste or smell, seizures, strokes, loss of consciousness and confusion.
Researchers found a tiny "ghost blood vessel" by scanning the brain of the deceased in COVID-19, which is a dead cell that can't make blood flow, and it is also a sign of cognitive impairment, which may cause many risks, such as micro-stroke.
It is worth noting that COVID-19 not only invaded the brain, lungs and respiratory tract, but also invaded other organs such as the heart, liver, kidney and digestive tract. The damage caused by COVID-19 is not only the lungs, but also the diseases of all organs.
Experts pointed out that in the face of COVID-19, symptomatic treatment and antiviral treatment should be taken for patients with mild illness, that is, through drug intervention, the symptoms of patients can be alleviated, so as to prevent them from developing into severe or even critical diseases, thus shortening the course of disease and improving the cure rate.
How did COVID-19 damage the cognitive function of the brain? A new study shows that COVID-19's patients may have "cognitive impairment" lasting for several months, which is also called brain fog.
My mind is like a fog, in a daze.
Mental retardation, slow response, memory will also be significantly reduced.
The key point is that this kind of brain fog not only appears in critically ill inpatients, but also appears in some mild patients.
JAMA Network Open magazine published this study, and nearly a quarter of COVID-19 patients registered in Mount Sinai health system have some memory problems.
"In this study, we found that the frequency of cognitive impairment was relatively high after patients were infected with COVID-19 virus for several months.
Obstacles in executive function, processing speed, category fluency, memory coding and recall are the main obstacles for inpatients. "
The researchers wrote: "This model is consistent with earlier reports describing executive dysfunction syndrome after COVID-19's disease, and has a considerable impact on occupational, psychological and functional outcomes. "
Another study published in The Lancet Psychiatry in April this year found that as many as one third of COVID-19 patients have long-term mental health or neurological symptoms.
The Centers for Disease Control and Prevention listed the difficulty of thinking or concentrating on the list of sequelae of COVID-19-sometimes called "brain fog".
Sequela of COVID-19 refers to a series of new, recurrent or persistent health problems that may appear within 4 weeks or longer after people are infected with COVID-19 virus for the first time.
According to COVID-19 patients suffering from "brain fog", this feeling is like "brain suddenly shut down".
One second they were chatting with others, and suddenly there seemed to be a vacuum in their brains.
Their thoughts have disappeared, and they can't remember the content and thoughts of the previous chat.
The researchers found that 15% of the respondents had phoneme fluency problems when speaking; 16% people have problems with their execution ability; 18% people showed impaired cognitive processing speed; 20% people are slow in dealing with categories or lists; Among other cognitive disorders, 23% people have problems in memory and recall, and 24% people have problems in memory coding.
The mechanism of brain damage caused by coronavirus pneumonia-19 is becoming more and more clear.
New evidence suggests that COVID-19 (novel coronavirus) may attack the brain in more than one way:
It can directly attack specific brain cells, reduce the blood supply of brain tissue, and induce immune molecules that will damage brain cells.
China scholars at the University of Pennsylvania once revealed in an interview:
"The sequelae of the COVID-19 epidemic may take 1 ~ 3 years to appear."