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Jurassic oxygen concentration paper
The essence of oxygen poisoning: high-purity oxygen acts as an oxidant in organisms, causing oxidative aging of cells, reacting with cell oxidase to generate hydrogen peroxide, and then reacting with biological protein to generate lipofuscin, which is the main component of senile plaque.

3% of the oxygen normally inhaled by human body is converted into active oxygen (high oxidation), which leads to aging. A larger proportion of oxygen atoms in high-purity oxygen will be converted into high oxidation active oxygen atoms, which will accelerate aging and cause poisoning. (Poisoning by hydrogen peroxide and lipofuscin)

It is toxic to all cells in the pure oxygen environment of 0.05MPa (half atmospheric pressure). If inhaled for a long time, "oxygen poisoning" may occur. The capillary barrier of the lung is destroyed, which leads to pulmonary edema, pulmonary congestion and bleeding, which seriously affects the respiratory function, and then leads to organ hypoxia and damage.

In the pure oxygen environment of 0. 1 MPa( 1 atmospheric pressure), people can only survive for 24 hours, and pneumonia will occur, which will eventually lead to respiratory failure and suffocation.

In the high-pressure pure oxygen environment of 0.2 MPa(2 atmospheres), it can stay at most 1.5 hours -2 hours, which will cause brain poisoning, disordered life rhythm, mental disorder and memory decline.

Under the oxygen of 0.3 MPa(3 atmospheres) or even higher, people will have brain cell degeneration and necrosis, convulsions and coma within a few minutes, leading to death.

People with 0.05mpa pure oxygen can exercise normally for a few days, and then the above symptoms will appear. Four hours in 0. 1 1mpa pure oxygen (99% is considered as pure oxygen, there is no difference) is enough to cause pulmonary edema, dyspnea and visceral injury. 24 hours is the limit of survival, and it is harmful for normal people to stay 1 minute in that environment.

⑴ Individual differences and individual physique differences (see below for details): Different individuals have great differences in sensitivity to high concentration oxygen. Even the same individual's tolerance to oxygen fluctuates greatly in different States.

⑵ CO2: Increase the concentration of CO2 in inhaled air and promote oxygen convulsion.

⑶ Labor intensity: The increase of labor intensity promotes the occurrence of oxygen poisoning.

⑷ Temperature: High temperature can reduce the body's tolerance to hyperbaric oxygen. Low temperature can increase tolerance to a certain extent, but if it is too low, it will cause muscle trembling and consume more energy, and the tolerance will also decrease.

5. Mental factors: mood swings, mental stress, lack of sleep, etc. Will reduce the body's tolerance to hyperbaric oxygen.

Oxygen poisoning accidents are common in aerobic diving.

However, 100% pure oxygen can be used to inhibit early sepsis, which is proved by mouse experiments. Generally, the medical oxygen content is lower than 60%, and it is still aimed at people with difficulty breathing.

About 300 million years ago, the oxygen content in Jurassic air was only 30%, and now it is 2 1%. High oxygen content enables giant creatures such as dinosaurs to breathe fully to survive, and there are also giant insects. In the historical period of our life, the oxygen content is gradually decreasing. According to the law of natural selection, in the period of decreasing oxygen content, the size of organisms is changing to small size, that is, the larger organisms are more difficult to adapt to low oxygen content (related to respiratory surface area and oxygen transport), that is, the smaller organisms are more sensitive to oxygen poisoning.

The higher the purity of oxygen, the greater the pressure and the easier it is to cause poisoning.

I don't know what you want with this question. Anyway, don't inhale high-pressure pure oxygen, it will only make you die faster. Severe patients do not easily use pure oxygen.

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