Generally speaking, positive results are more eye-catching because of deeper research, and magazines are more willing to accept publication. However, if the sample size of negative results is not large, it is more difficult to publish SCI journals, depending on your luck.

The Lancet published a research paper with negative results, which proved that the view that oral probiotics were used to prevent antibiotic-associated diarrhea in the past was wrong with strict control. But such a high-end journal has a sample size of 3000.