Project undertaken: 1. Experimental and clinical study on percutaneous coronary intervention for borderline unstable lesions. Shandong province's science and technology development plan 2008-20 1.08 million yuan ranked first. 2. Prospective randomized, double-blind placebo-controlled application of Tongxinluo in the intervention of carotid plaque Multi-center clinical research collaboration project (key project of hospitals directly under the Ministry of Health) 2009-20112000 Yuan collaboration leader 3. Popularization and Application of Non-invasive Early Warning Method for Atherosclerosis Cardiovascular Events Collaborative Project (Health Industry Research Project) 20 10-2065438+ Person in charge 4. Comparison of percutaneous coronary intervention and drug therapy for borderline unstable coronary artery disease with normal blood flow reserve fraction. Papers published by Shandong Science and Technology Research Plan: 1. Relationship between the expression level of mononuclear factor -kB protein in peripheral blood and the characteristics of coronary artery lesions in patients with acute coronary syndrome. China Journal of Geriatrics, 2009, 28(9), 7 12 Newsletter 2. Evaluation and management of myocardial no-reflow after coronary intervention China Journal of Clinicians 2009,7 (3): 1 082 First academic award and honorary title:1. Study on the relationship between no-reflow and levels of NF-κB, AP- 1 and GR in patients with acute myocardial infarction after emergency PCI (2009) 2. Effect of direct coronary stent on myocardial no-reflow after acute myocardial infarction. Third Prize of Shandong Science and Technology Progress 20 1 1 (second place). 3. The experimental research on gene and drug therapy for stabilizing vulnerable plaque won the second prize of Yantai Science and Technology Progress Award.