Aiming at how to stimulate students' interest in learning chemistry, combined with the psychology of middle school students, this paper makes some explorations around the following five aspects: establishing a new teacher-student relationship is the basis for stimulating students' interest in learning; Improving teachers' comprehensive quality is an important factor to stimulate students' interest in learning; Creating an emotional atmosphere with humanistic atmosphere in class is a powerful means to stimulate students' interest in learning; Actively creating autonomous classroom is an effective way to stimulate students' interest in learning; Using flexible and diverse teaching methods is an effective way to stimulate students' interest in learning. ? Keywords new teacher-student relationship; Comprehensive quality; Loose; Harmony In today's promotion of quality education, teachers are no longer simply imparting knowledge, and students are no longer passively accepting knowledge. In teaching, students are the main body of learning and development, and teachers should give necessary guidance and help around this main body. To make students change passive learning into active learning, it is mainly to stimulate their interest in learning. Interest is the best teacher for students, the most authentic and vivid psychological component of learning motivation, and the most important power source for students to learn well without any compulsion. Therefore, how to stimulate students' interest in chemistry teaching is an important way to improve teaching quality. ? 1. Establishing a new relationship between teachers and students is the basis of stimulating students' interest in learning. Establishing a new teacher-student relationship is the premise and condition of the new curriculum implementation and teaching reform, and it is also the content and task of the new curriculum implementation and teaching reform. It is a real communication between people and the result of mutual care between teachers and students. Teachers must establish the concept of equality, including two contents: first, although teachers and students have different responsibilities and tasks in education, their status is equal; Second, although students have different personality characteristics and academic achievements, their status in the eyes of teachers should be equal. The symbol of equality is respect. To respect students, we must learn to tolerate, accept and appreciate students, especially those with poor learning foundation and loose discipline, so that every student can gain self-confidence and a sense of accomplishment. ?