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abstract:
Pharmaceutical engineering is a new engineering and technical discipline devoted to pharmaceutical research, and it is an interdisciplinary subject. It is mainly developed on the basis of rapidly developing disciplines such as chemical engineering and pharmacy. In the process of development, biotechnology, chemical engineering technology and biotechnology have gradually extended. Due to the rapid development of economy and science and technology in China, the technological innovation of pharmaceutical engineering is facing great challenges and opportunities. This paper mainly discusses the introduction, innovation, reform and production optimization of pharmaceutical engineering technology, the reasonable design of pharmaceutical experiments and the significance of pharmaceutical engineering technology innovation and reform.
Key words:
Pharmaceutical engineering technology; Innovation; Reform; Meaning;
Introduction:
Pharmaceutical engineering is a comprehensive subject [1], involving research in many fields. It is also a practical subject that needs specific research. In recent years, great changes have taken place in China's economy. With the development of medical engineering, medical engineering plays an important role in the whole social system and national economy, and people pay more and more attention to it. In today's society, after solving the problem of food and clothing, health problems have attracted much attention, and pharmaceutical engineering is also an important part of people's health. With the increase of people's demand, pharmaceutical engineering is facing the challenge of reform and innovation. Without reform and innovation, there will be no development, so reform and innovation are the only way [2]. Reform new pharmaceutical technology and develop new products to meet people's growing needs and not be eliminated.
1, Introduction to Pharmaceutical Engineering Technology
In fact, the overall level of China's pharmaceutical industry is not high, mainly because: China's pharmaceutical technology and R&D capabilities are far behind other developed countries, mainly in pharmaceutical synthesis technology; There are many problems in the production equipment and technology of pharmaceutical technology in China, which seriously affect the quality and output of pharmaceutical products. It is an urgent project to carry out technological innovation in pharmaceutical industry, and its innovation is related to the further development of China's economy, people's livelihood and science and technology. According to the actual situation of pharmaceutical engineering in China, it mainly includes technology and equipment.
Process analysis of 1. 1.
It is the technical analysis of pharmaceutical process. The simulation process of pharmaceutical production process is pharmaceutical process, which involves the application of many disciplines, such as mathematics, chemistry, physics, biology and so on. For the specific manufacturing process of a drug, first, the combination experiments are carried out according to the chemical properties of various components, and many comparisons are made to find out the most fundamental factors between drugs and diseases, find out the best compatibility, and minimize risks and side effects, and then the batch production can be realized through the audit of the pharmaceutical department. For synthetic drugs, we should follow the scientific design, proceed from the characteristics of the disease itself and synthesize the target molecules, follow the logical knowledge of chemical reactions, and finally design a scientific synthetic route to synthesize drugs. Optimization of pharmaceutical batch processing technology. Relevant personnel of pharmaceutical enterprises should establish a complete production line according to the process characteristics, and analyze the uniqueness of each process in detail to ensure the accuracy of each link. With the development of technology and the introduction of new equipment, it is very important to optimize the process from the aspects of output and quality to maximize economic benefits. Drug quality supervision and management. For pharmaceutical companies, quality issues are particularly important, and there can be no mistakes. Pharmaceutical products are related to people's life and health. Therefore, the supervision of pharmaceutical engineering technology is stricter, and it is necessary to establish a set of perfect drug quality supervision system, and then carry out the work in accordance with relevant state regulations.
1.2 equipment analysis.
It is the equipment for analyzing the pharmaceutical process. The function of pharmaceutical equipment determines the smooth implementation of pharmaceutical engineering technology. In today's society, the promotion of Good Manufacturing Practices (GMP) is getting stronger and stronger. For the selection and use of pharmaceutical equipment, there are the following points: First, we should strengthen the research on pharmaceutical synthesis technology, and put into work from the aspects of equipment design concept, equipment selection and use, equipment installation and operation, but we should also meet the requirements of domestic pharmaceutical production quality and keep approaching the requirements of international high standards. Second, for pharmaceutical equipment, we should start with the management of production links. Meet the requirements of drug synthesis process, and then carry out basic treatment such as separation, concentration, reduction and oxidation of drug components. Therefore, it is imperative to develop new equipment that is easy to clean, disinfect and maintain, which can not only effectively reduce mistakes in pharmaceutical industry production, ensure high efficiency, but also better reduce environmental pollution.
2, pharmaceutical engineering technology innovation
2. 1 Strengthen the selection and training of pharmaceutical talents.
Drug synthesis technology plays an important role in the whole pharmaceutical engineering technology system. Due to personnel factors, the development of pharmaceutical engineering technology in China is generally slower than that in developed countries. China's modern pharmaceutical industry technology started late, mainly due to the lack of perfect talent training system and professional knowledge and theory. China lacks theoretical guidance and practical environment for cultivating innovative talents in pharmaceutical industry. Therefore, China must attach importance to and promote the status of high-tech pharmaceutical talents, build the necessary talent training environment, and thus establish China's pharmaceutical engineering technology model.
2.2 Learn from the production experience of foreign developed countries.
With the development of social economy and science and technology, all industries do not exist in isolation, but are linked by a network of relationships. By introducing pharmaceutical engineering technology from foreign developed countries and combining their theories, experience, technology and equipment, we can make up for the technical defects of China's pharmaceutical industry and actively move closer to the international advanced level.
3. Methods of pharmaceutical engineering reform and production optimization
3. 1 pharmaceutical engineering technology development.
The development of pharmaceutical engineering technology has brought dawn to pharmaceutical engineering in China. Scientific researchers use the professional knowledge in this field to solve the problems existing in the pharmaceutical process with correct methods and means. Expert training is a priority. In the process of pharmaceutical engineering, it is necessary to select skilled professionals, carry out exchanges between higher education and production bases, and carry out technological innovation in pharmaceutical engineering production. For the cultivation of talents, we can attach importance to the optimization and innovation of technology. In order to prepare for the future pharmaceutical engineering, people need to increase the development of human resources and cultivate high-tech talents, and the training direction of talents determines the future development direction of pharmaceutical engineering [3,4].
3.2 Strengthen the theoretical experiments and practical activities of pharmaceutical engineering.
Unique and effective product development is a favorable embodiment of this project. Although a production process is monotonous, these steps should be carried out and summarized according to the process. During the experiment, there are repeated basic experiments of pharmaceutical engineering and many chain experiments, which require timely summary. Use technology to deal with different schemes, so as to realize their functional value and ensure that they are harmless to human body. For the participants in the experiment, it is necessary to carry out the workflow under the premise of physical safety, and this work can not tolerate any omissions and carelessness. In terms of technology, repeated experiments need to constantly update related concepts and experimental procedures, so technical experts need to carry out technological innovation, and then optimize and reform the pharmaceutical production process. Perfect combination of theory and practice, perfect technological innovation.
3.3 Summarize and learn new knowledge and skills.
Technological innovation mainly depends on biotechnology and chemical engineering technology, as well as scientific research and pharmaceutical engineering. The introduction and absorption of foreign advanced technology will often affect the development direction of innovative pharmaceutical engineering technology. Combining the characteristics of China's own development with foreign advanced technology is conducive to the cultivation and development of innovative thinking and scientific research personnel. In order to develop the pharmaceutical industry, it is necessary to promote the study summary and the study of new information and apply them in practice. There are some similarities in use. The birth of new technology has an absolute advantage in the current pharmaceutical preparation market, and promotes China to actively move towards international pharmaceutical engineering. Therefore, the implementation of innovation and optimization technology will have a multiplier effect on pharmaceutical engineering.
4. Reasonable and scientific design of pharmaceutical experiments.
4. 1 Try to choose raw materials and schemes with low toxicity.
In the process of drug experiment, it is necessary to minimize the use of harmful substances and try to use less toxic substitutes to reduce the harm to human body and environmental pollution.
4.2 Optimize and adjust the experimental outline.
Some experimental products can be reused and recycled, thus reducing the generation of waste and the waste of reagents. Pharmaceutical engineering majors need to learn analytical chemistry experiments, learn basic experimental skills, conduct reasonable experiments through artificial synthesis and identification, and constantly try to combine experiments on synthetic products.
4.3 Minimize the use of reagents in micro-experiments.
Reduce the reagents of micro-experiment to achieve the experimental purpose. Micro-experiment refers to the inferior laboratory equipment and miniaturized drugs that track laboratory equipment under experimental conditions. This kind of micro-experiment can effectively reduce the cost and reagent consumption, thus reducing the pollution to the environment and shortening the experiment time. We should take a cautious and serious attitude when using micro-scale green chemistry experiments. Nowadays, the education sector strongly advocates autonomous teaching, and it is necessary to change the traditional education mode to instill, let students know about the experimental device and realize the autonomy of experimental design.
5. Significance of innovation and reform in pharmaceutical engineering.
5. 1 lead advanced technology and guide the way of pharmaceutical field.
Pharmaceutical engineering, biopharmaceuticals, pharmaceutical engineering and pharmaceutical preparations have developed from the initial appearance to a new situation. We can find the social status and economic progress of pharmaceutical engineering from many fields and levels, which shows that the reform and innovation of pharmaceutical engineering has made great achievements. From the blank field of pharmaceutical technology, to the emergence of chemical raw materials, to China's reform and opening up, and finally to applying for international patents, China pharmaceutical engineering has embarked on a road of continuous progress. In recent 50 years, pharmaceutical engineering industry has been mainly carried out in China, and China is also a major raw material producer. Market demand and development opportunities have promoted the reform and innovation of pharmaceutical engineering closely related to people's lives.
5.2 Medical innovation to improve the status of China.
The innovation of pharmaceutical technology and the demand of drug treatment have greatly promoted China's position in international pharmaceutical engineering, which can improve people's living standards and treatment effect. Nowadays, the pharmaceutical market is facing innovation, which can promote the vigorous development of the pharmaceutical industry. For some domestic technical foundations, the conditions for reform and innovation cannot be met. The pharmaceutical industry is in line with international standards, which makes China step on the road of internationalization. China pharmaceutical engineering research has enough room for development in China market. Due to the lack of technology, we can't gain a firm foothold, so the development of China's pharmaceutical industry is relatively backward. In order to promote the pharmaceutical engineering technology of new drugs, we can only constantly improve people's comprehensive strength and innovate and reform.
6. Conclusion
Since the reform and opening up, China's economy has undergone earth-shaking development, and the improvement of people's living standards has enabled people to maintain their health more and more. Drug safety involves health problems, so it has become a topic of concern to the whole society. Therefore, if China pharmaceutical engineering wants to develop, it must be constantly improved and innovated to meet the requirements of national laws and market recognition and gain people's trust. Actively innovating pharmaceutical engineering technology can not only reduce the waste of resources, but also protect the environment and reduce damage. Innovate according to national standards, deepen research, develop healthy and effective drugs, and relieve people's suffering. Improve the level of pharmaceutical production through unremitting efforts. In China's pharmaceutical industry, the development goal of biopharmaceuticals is mainly to innovate chemistry through joint engineering, so as to achieve the purpose of innovation and reform.
refer to
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[2] Li Hua, Hu, Liang, Zhang Yadong. Research and practice on the reform of training mode for pharmaceutical engineering professionals [J]. Chemistry Higher Education .201(04): 2-6.
[3] Tan Ni, Nie Changming, Yuan Yali, Xiao Xinrong, Tao Liming, He Jun. Research on practical teaching system of new pharmaceutical engineering professionals [J]. Chemistry Higher Education.2010 (04): 2-5.
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