First of all, withdrawing the manuscript will seriously affect the author's academic reputation. SCI is an internationally recognized authoritative journal, and its published articles have high academic value and influence. Once the article is withdrawn, it means that the article has serious academic misconduct or research quality problems, which will cause serious damage to the author's academic reputation.

Secondly, withdrawing the manuscript may make the author lose some important academic opportunities. For example, in the process of recruitment and promotion, some academic institutions and universities will refer to the applicant's scientific research achievements, including the quantity and quality of published papers. If the author's paper is rejected, it may affect their application results.

In addition, the withdrawal of the manuscript may also affect the author's research funding. Many scientific research projects need published papers as results. If the paper is withdrawn, it may lead to the failure of the project and even affect the application for subsequent research funds.

However, it is worth noting that although the withdrawal of the manuscript will have a negative impact on the author's research career, it does not mean that the author's academic career is over. As long as the author can learn from his mistakes, adhere to a rigorous scientific research attitude and continue to carry out high-quality research work, it is still possible to restore and enhance his academic reputation. At the same time, academic circles generally recognize the importance of withdrawing manuscripts, and many journals and academic institutions are striving to improve the quality of papers and reduce unnecessary withdrawing manuscripts.