A preliminary study on establishing insulin transgenic mouse strains by using inducible gene expression system, which is supported by the National Natural Fund of China.
Provincial key research projects
Study on introducing antimicrobial peptide gene with mouse sperm stem cells as carrier
Study on the expression of human insulin in tussah by nuclear polyhedrosis virus.
Establishment of transgenic platform for experimental animals and gene knockout
Study on the expression of human insulin gene with tussah as bioreactor
Establishment and mechanism of SV40T transgenic mouse model with deletion of P53 and Rb binding function.
"Study on establishing a transgenic rat model of kallikrein", etc.
Representative papers:
Study on the establishment of transgenic indicator system of green fluorescent protein, China Journal of Experimental Animals,1998,8 (1).
Construction of baculovirus expression vector of human insulin gene and its expression in Sf9 cells, China Veterinary Journal, 200 1, 3.
Effect of the first intron on the expression of human insulin gene in BHK cells, China Journal of Experimental Animal Science, 2002, 12(5).
Comparative study of liposome transfection and calcium phosphate transfection, China Journal of Experimental Animal Science, 2000, 1.
Experimental study on the expression of human insulin gene in BHK cells and its hypoglycemic effect, Journal of China Medical University, 2003.
Editor-in-Chief Monograph: Newly Edited Laboratory Animal Science
2. Teaching:
To undertake the optional courses "Medical laboratory animal science" and "model animal Choice" for undergraduate classes in our school from 2000 to 2002.
3. Academic positions:
Vice Chairman of Liaoning Experimental Animal Society; Editorial Board of Journal of Experimental Animal Science