Biosafety measures are very important for pig epidemic disease control, involving many aspects, including congenital factors such as site selection and layout, production technology, facilities and equipment. Biosafety measures for disease control in the production process mainly include: ① A disinfection room (pool) should be set at the entrance of the pig farm, and the living area, production area and auxiliary production area in the pig farm should be strictly separated, and the production area must be relatively closed; ② Breeding pigs shall not be purchased from pig farms with unknown health status, and newly introduced pigs shall be quarantined for 30-60 days before entering the herd; ③ Adhere to the breeding mode of self-propagation, self-support and all-in and all-out; ④ Dogs, cats and other pets and other livestock and poultry shall not be kept in the pig farm, and mosquitoes, flies and rodents shall be removed regularly; (5) it is forbidden to buy pork and other slaughter products from other places; ⑥ Select appropriate feed, and the purchased feed must be dried and disinfected in the warehouse 1 week before use; ⑦ All tools used on site must be fumigated and disinfected before they can be brought in. It is forbidden to mix tools in different areas. ③ Strictly control personnel entering and leaving the pig farm, and only allow production management personnel to enter the pig farm. Workers on vacation or going out must be isolated for 72 hours, and are allowed to enter the production area after routine disinfection, thorough shower and changing clothes; @ Regularly disinfect the internal and external environment of the pig farm, and implement disinfection measures for the pigs in the pig house; Attending sick pigs should be isolated and treated in time, and dead pigs should be burned or buried deeply; ① Select qualified vaccines, vaccinate pigs scientifically and reasonably in strict accordance with immunization procedures, and monitor the immunization effect regularly; ② Regularly carry out drug prevention and health care for pig farms.