Professional Laboratory of Dioxin Detection, Ministry of Health, Shenzhen Key Laboratory of Medicine. The laboratory invested nearly 10 million yuan, established a technical echelon with doctors and masters as the main body, equipped with gas chromatography/high-resolution dual-focus magnetic mass spectrometry, and built a technical platform for ultra-trace detection of persistent organic pollutants represented by dioxins. It can be used for qualitative and quantitative detection of 17 kinds of dioxin isomers (PCDD/Fs), 37 kinds of polychlorinated biphenyl isomers (PCBs) and 7 kinds of polybrominated diphenyl ether compounds (PBDEs) which are commonly detected in the world. Sample substrates that can be analyzed include: food, food additives, feed, waste incinerator flue gas, fly ash, sediment, soil, water and chemical products. In recent years, he has undertaken and presided over 8 scientific research projects funded by the National Natural Science Foundation, Guangdong Province and Shenzhen City. Participated in 8 national scientific research projects, such as the Tenth Five-Year Public Relations Scientific Research Project of the Ministry of Science and Technology, National 973 and National Key Technologies of Food Safety. Won the second prize of "China Medical Science and Technology Award" and the third prize of Shenzhen Science and Technology Progress Award 1 item; Declare 1 invention patent. Academic monograph 1 has been compiled and published, and more than 30 academic papers have been published, including 6 papers included in SCI. In addition, it has the qualification to recruit master students independently and cooperate to recruit doctoral students. More than 10 graduate students and doctoral students have been trained. It has played an important role in ecological security and food safety guarantee for many times.
2. Health toxicology laboratory
Guangdong "Eleventh Five-Year" Medical College, Shenzhen Key Laboratory, Shenzhen Key Laboratory of Medicine. The laboratory is now affiliated to the specialized committee of biochemistry and molecular toxicology of China Toxicology Society, the specialized committee of health toxicology of Guangdong Preventive Medicine Association, the postdoctoral research base of Sun Yat-sen University and the postdoctoral innovation base of Shenzhen. The laboratory has formed a talent echelon and research team with doctors and masters as the main body. The key research directions are: the molecular mechanism and biomarkers of chemical pollutants' damage to the body, as well as the adaptation and tolerance mechanism of the body. Professor Zhuang, the leader of laboratory discipline, is currently the chairman of China Toxicology Society. Both Sun Yat-sen University and Central South University have appointed professors and doctoral supervisors. At present, the laboratory has more than 22 million yuan of advanced instruments and equipment for the overall level detection and research of cells, genomes, epigenomes, protein group and experimental animals, and also has an experimental animal center with SPF and general experimental animal license issued by Guangdong Science and Technology Department. At the same time, the laboratory is responsible for accepting the entrustment of customers to conduct toxicity testing and safety evaluation on food, cosmetics, disinfectants, disposable sanitary products and chemicals. In the past five years, the laboratory has undertaken 4 1 national, provincial and municipal scientific research projects, including 8 national natural science foundation projects 10 (independently undertaken and 2 cooperative units); National 973 Project: 2 (sub-project responsible unit); National 863 Project: 1 (cooperative unit); Provincial Natural Science Foundation Projects: 5 projects (4 independently undertaken, 1 cooperative unit); Subject of Provincial Health Department: 2; Municipal Science and Technology Plan Project: 2 1 (including 3 key projects). Since 2004, it has won national, provincial and municipal science and technology achievement awards 12, including Guangdong provincial science and technology progress special award 1, Guangdong provincial science and technology progress second prize 1, Chinese medicine science and technology second prize 1, Guangdong provincial science and technology progress third prize1,and Shenzhen scientific and technological innovation. Published 375 academic papers in national journals, 22 journal papers included in SCI, and 13 international conference papers. There are 20 doctoral students, 23 master students and 2 postdoctoral students.
3. Molecular Biology Laboratory
Shenzhen Key Laboratory of Medical Molecular Biology is mainly engaged in the research and development of vaccines and diagnostic reagents for tropical diseases, molecular epidemiology of chronic non-communicable diseases, molecular mechanism of human and animal diseases, and cancer prevention. It has a technical platform integrating tropical disease research, diagnosis, teaching, prevention and control, and is qualified to recruit master students independently, cooperate with doctoral students and post-doctoral mobile stations. At present, it undertakes research projects of National Natural Science Foundation, Guangdong Natural Science Foundation, Shenzhen-Hong Kong Innovation Fund and key projects of Shenzhen Science and Technology Plan. The main research direction is: 1) research on exon-related genome of China yellow race; 2) Study on stroke-related functional genes and gene therapy in China yellow race; 3) develop a biosensor and its composite gold-labeled chromatographic kit for on-site rapid diagnosis of food pollutants; 4) To study the preventive and therapeutic effects of enterotoxin on cancer; 5) Preparation and application of monoclonal antibody against Angiostrongylus cantonensis circulating antigen; 6) Study on comprehensive prevention and control technology of toxoplasmosis. Over the past five years, more than 240 academic papers have been published at home and abroad, including many papers published in internationally influential journals such as Emerging and Infectious Diseases, Infection and Immunity, BBC, Cancer Research, International Parasitology, Parasitic Immunity and Parasitic Research. Won a number of national patents and provincial and municipal scientific and technological achievement awards. Training nearly 50 doctoral and master students for the country.
4. AIDS laboratory
Laboratory of AIDS Confirmation of Ministry of Health Shenzhen Key Laboratory of Health System. Responsible for the city's AIDS epidemiological monitoring and epidemic disposal, laboratory screening and confirmation, treatment drug information management, related technology research and promotion, policy research and so on. At present, a talent team with senior professional titles and highly educated personnel has been formed, with large-scale equipment such as flowmeter, automatic nucleic acid extraction workstation and protein extraction workstation. In the past three years, he has undertaken more than 20 national, provincial and municipal scientific research projects and international cooperation projects. His main directions include: AIDS-related population survey, molecular epidemiology, basic virology research, mother-to-child transmission interruption, drug resistance analysis, etc. , published nearly 10 SCI papers and applied for national invention patent 1 item. At present, the laboratory has established close cooperative relations with more than ten famous universities and research institutions at home and abroad.
5. Genetically modified laboratory
Few units in the national disease control system can engage in transgenic detection and research. Investment1100,000 yuan for construction. At present, technicians of food hygiene and safety, nutrition and health care, genetic engineering, molecular biology and other related majors mainly carry out the standard research on the safety risk assessment of genetically modified organisms and genetically modified foods, and undertake the research work on the safety inspection technology of genetically modified foods issued by Guangdong Science and Technology Department, Health Department and Shenzhen Science and Technology Bureau. Obtained two national invention patents of "genetically modified detection", formulated six local standards of Shenzhen and Guangdong, such as Requirements and Evaluation of Food Safety of Genetically Modified Organisms and Inspection Methods and Safety Requirements of Genetically Modified Foods, compiled and published four relevant academic monographs, and published 33 related research papers, including 3 papers included in SCI, which won the third prize of Guangdong Science and Technology Progress Award 1 item and 2 Shenzhen Science and Technology Innovation Awards successively.
6. Microbiological Reference Laboratory
Guangdong province "Eleventh Five-Year Plan" medical specialty, Shenzhen key medical laboratory; It has three experts who enjoy special government allowances and a group of professional teams with senior titles and highly educated technicians. It is equipped with a number of domestic advanced biosafety laboratories and nearly 20 million kinds of advanced instruments and equipment, and has established a relatively complete detection and research platform for immunology, etiology, cell biology and genomics, providing laboratory diagnosis and reference inspection services for the study of pathogenic microorganisms and the emergency treatment of infectious diseases such as SARS, avian influenza, A H 1N 1 in the city. In the past five years, he has presided over more than 20 research projects of the National Natural Fund, major national science and technology projects and provincial and municipal projects, and won many Chinese medical awards, provincial and municipal scientific research achievement awards and three national patents. .
7. Physical and chemical testing laboratory
Have a group of professionals with senior technical titles and doctoral and master's degrees; It is equipped with more than 20 large-scale precision analytical instruments such as liquid chromatography/tandem mass spectrometry, liquid chromatography /ICP-MS and gas chromatography/mass spectrometry. It integrates daily detection and research and development of new technologies and methods, and has carried out more than 400 detection items such as melamine, Sudan red, malachite green and acrylamide. At the same time, it also carries out the prediction, early warning and analysis of health hazard factors of places and health-related articles; Iodine deficiency disorders, food nutrition examination; Detection of total α and β radioactivity; Responsible for emergency inspection of public health emergencies. In recent five years, he has undertaken 24 projects of International Atomic Energy Agency (IAEA), Guangdong Natural Science Fund, Guangdong Medical Science Fund and Shenzhen Science and Technology Fund, participated in national standard research project 19, and won Shenzhen Science and Technology Innovation Award and Shenzhen Standard Innovation Award 1 respectively.