According to relevant data and folk experience, Sophora alopecuroides has a good effect in treating stomach diseases, and related experiments show that Sophora alopecuroides can detoxify nicotine, so it is inferred that it may contain 1 substances that can neutralize nicotine. Finally, it is concluded that there are 1 endogenous substances in human body, 1 is similar to nicotine, and 1 is similar to a substance in bitter vegetables. In general, the two neutralize each other; If the content of nicotine analogues is high, it will cause stomach problems.

Key words: sonchus oleraceus, nicotine, endogenous substances, stomach diseases

Text:

There are many bitter vegetables in my hometown. Some people use them to treat stomach diseases, and the effect is very good, so I became interested. Through the study of them, I found that it really has a lot to pay attention to. Www.lwkoo.cn graduated from paper net.

Sonchuso 1eraceusL。 Ix-erischinssis (Thunb。 ) Nakai is true. Nine. denticulata (Houtt。 )Stebb。 Chicory 1 eraceusl, also known as Ix-Erischinssis, Ix. Bitter dish 1-2 panicum miliaceum. Every hundred grams of young leaves contain 9 1 g of water, 0.8g of protein/kloc-0, 0.5g of fat, 4g of carbohydrate, 0/20mg of calcium, 52mg of phosphorus, 0/.79mg of carotene and 20.18 of vitamin B. Bitter vegetables taste bitter and cold, and have the effects of clearing away heat and toxic materials and cooling blood. Can be used for treating dysentery, jaundice, bloody stranguria, hemorrhoid and leakage, and swelling. "southern Yunnan materia medica" contains "cold serum is hot, cold stomach, please accumulate in the abdomen to facilitate urination." Compendium of Materia Medica contains "Treating Hemorrhoids and Hemorrhoids with Blood". It is not suitable for people with spleen and stomach deficiency and cold. [ 1]

The fact that bitter herbs treat stomach diseases has been confirmed by many people and the effect is good; Bitter vegetables can improve the taste and strengthen the stomach. If you eat bitter vegetables in spring, you can strengthen your stomach, improve your digestive function and resist the summer heat. [2]

In recent years, experts have found that bitter herbs contain components combined with nicotine, so bitter herbal tea is the best drink for smokers or passive smokers. The following is an example of 1: In the early 1960s, people often went to the wild to catch lizards to satisfy their hunger. My grandfather told him that the white juice in the root of Sophora alopecuroides can detoxify. 1 time, this man caught a lizard, dug out smoke oil from grandpa's long pipe and put it in the lizard's mouth. It soon fainted, then put the white juice of the bitter vegetable root into its mouth, and the lizard came back to life in the blink of an eye. From this point of view, eating more bitter vegetables and drinking more bitter tea is very beneficial to your health.

Some people have done the following detoxification experiments of bitter vegetables on nicotine:

1. Brief introduction of chicory selling vegetables and suggestions on problems.

Geerusderiovlolo, also known as vegetables and bitter vegetables, is a perennial herb of Compositae, with phimosis at the base and purple and yellow tongue-shaped flowers at the lower part, which is widely wild in China. There is white milk in its stems, leaves and taproots. The juice turns from white to dark brown when it comes into contact with air. After 1, it will solidify into colloid, making the seedlings edible. Its medicinal function has long been included in the treasure house of traditional Chinese medicine. Patrinia scabra is a whole plant, which contains coumarins and steroids. It is mainly used to treat intestinal pain, sores, swelling and pain, enteritis, dysentery, postpartum hemorrhage, hemorrhoids and other diseases. It can detoxify mosquitoes, flies and insects, and has the effects of clearing away heat and toxic materials, reducing swelling and expelling pus, and removing blood stasis. According to our experimental results on several animals, selling vegetables with chicory can also detoxify nicotine. We think this 1 project is worth studying and discussing. Obviously, tobacco contains a lot of nicotine, and smoking is recognized as harmful to human body. However, despite the repeated advocacy of "no smoking" in the world, they all failed, which is obviously an irreconcilable contradiction of 1. We can imagine that this kind of lettuce, which is abundant and easy to get everywhere, can be mixed into tobacco or directly taken by smokers, which can reduce the toxicity of nicotine in tobacco to human body, so it is of great significance and broad significance.

The following is the experimental summary of this 1 project on snakes, lizards and rats.

2, experimental materials and experimental process

L test materials

(1) Golden Snake with Black Eyebrows: also known as cauliflower snake. Reptiles, snakes. Captured in the west of Baotou.

(2) sand lizard: also known as toad-headed lizard, reptile, Iguanidae. There are fields in Baotou area.

(3) Mice: kept in animal houses.

(4) Oil accumulation due to smoke; Paste poked out of cigarette butts.

(5) Chicory milk for selling vegetables: collected from the suburb of Baotou and extruded from its stem.

(6) distilled water.

2. Experimental process

Test 1: Verify the snake death caused by nicotine. 1August 20, 990.

Subjects: snake, weighing 156g, with a body length of 0.65m, was not morbid before the test.

Test process and phenomenon: 0.004 g of fuming oil was dissolved in distilled water and injected into Shekou with a needle-free syringe. After the first injection of oil fume, it can still crawl 1.5m, and the drug takes effect after 3 1 sec. Observe its reaction: the body begins to spasm from the tail, then the neck becomes stiff, the pupil spreads and loses its luster, saliva flows out of the mouth, and then the whole body becomes stiff and falls to the ground in the mouth, and dies after 1 minute.

Experiment 2: To observe the detoxification effect of selling vegetables with chicory on nicotine. 1August 20, 990.

Subjects: snake, weight 178g, body length 0.7 1m, no pathological changes before the test.

Test process and phenomenon: First, 0.004g of smoke oil was injected into Shekou by test method 1. After 48 seconds, the drug took effect, and the snake reaction was basically consistent with the test 1. Immediately after the snake goes into shock, pry open Shekou with the scalpel handle and smear 0. Put fresh lettuce and milk into the snake's throat and take it with distilled water. Observe its reaction: after 4 minutes, the snake's tail first returns to softness. After 5 minutes and 30 seconds, the hand touched the snake and the snake became conscious. After 7 minutes, the head of the snake can be raised, the pupil gradually regains luster, and the arm swings in front of the eyes to make it dodge. After 8 minutes, the snake's neck returned to softness. 10 minute 12 seconds later, snakehead held its head high and twisted. The recovery process of snakes is just the opposite of poisoning.

Experiment 3: Observe the reaction of the mixture of tobacco oil and lettuce milk to animals. 1August 22, 990.

Experimental object: snake, weighing 203 grams and 0.8 meters long.

Dosage: 0.004 g, 0. Mixed lettuce and milk.

Process and Phenomenon: Inject 2ml of the adjusted mixture into Shekou. After 40 seconds, the snake has a slight abnormal reaction, which shows that it crawls slowly or stops crawling, and its strength is weak, but there is no big reaction. As time went on, the snake gradually returned to normal. After the test, you can continue to raise it.

Experiment 4: Function of Lactic Acid Gum in Lettuce. 199 1 year 65438+1October 20th

Subjects: Same as Experiment 3.

Medicine and dosage: 0.004 g of smoked oil is made into aqueous solution, and 0.008 g of lettuce milk block is made into solvent (it needs to be heated in porcelain crucible and dissolved after 2 hours).

Process and phenomenon: inject the smoky oil solution into Shekou by test 1 and observe its reaction, which is basically the same as the test 1. Then inject the milk lump liquid into Shekou in time. After 20 minutes, touch the snake and feel it. After 33 minutes, he waved his arm in front of the snakehead. The snake dodged, its body turned from stiff to soft, and its head was raised. After 45 minutes, you can crawl.

Experiment 5: Observe the response of sand lizard to nicotine. 1August 23, 990.

Test drug: same as test 1

Process and phenomenon: pry open the mouth of sand lizard with small wood chips and put 0.002 g (paste) of tobacco oil into its mouth. After 5 seconds, the tail and limbs twitched, the head was low, the mouth was open, and the hind legs were stretched 3 ~ 4 times, and they died after 40 seconds.

Experiment 6: Observe the reaction of mixed milk of nicotine and lettuce to sand lizard.

Medicine and dosage: 0.00 1g (paste) smoked oil, mixed with 0.002g fresh lettuce milk, without water.

Process and phenomenon: put the mixed medicine into the mouth of the sand lizard with small pieces of wood. Its phenomenon: it can still crawl quickly without poisoning.

Experiment 7: Observe the reaction of mice to nicotine. 199 1 year 65438+ October 23rd.

Test methods: oral and intramuscular injection.

Process and phenomenon: First, 0.002 g of oil fume was dissolved, then injected into the mouth of rats with a needle-free syringe, and there was no reaction after 20 minutes.

Dissolve tobacco oil 0.002 e, filter, take lml intramuscular injection, spasm immediately, and then die.

Experiment 8: Observe the reaction of nicotine mixed with chicory milk to mice. 1990 65438+1October 23rd.

Test method: intramuscular injection.

Process and Phenomenon: Dissolve 0.002g of smoked oil, mix it with 0.0042g of lettuce milk, filter it, and take lml for intramuscular injection. The results showed that after the injection, the mice could still run, their hind legs were slightly dragged, and their spirit was weakened, but they did not die.

Three. conclusion

1. Nicotine can poison and kill small animals, such as lizards, snakes and mice.

2. Nicotine mixed with chicory milk can degrade the toxicity of nicotine.

3. Chicory selling vegetable milk can alleviate nicotine toxicity.

4. The response of nicotine toxin to mammals (this is a single-fingered mouse) is far less rapid than that of amphibians (this refers to snakes and sand lizards), but it reacts quickly through intramuscular injection.

5. The plant milk sold by colloidal chicory can still degrade nicotine toxicity. [3]

Studies have shown that nicotine can act on the vagus nerve system, destroy normal gastrointestinal activities, relax pyloric sphincter, contract gallbladder, make alkaline bile easily flow back into the stomach, thus destroying gastric mucosa, and also promote the increase of gastric acid secretion, inhibit prostaglandin synthesis, thereby reducing gastric mucosal mucus secretion. These will damage the gastric mucosa and lead to stomach problems. [4]

It can be seen that sowthistle can not only treat stomach diseases, but also alleviate nicotine toxicity. From this, the hypothesis of 1 is obtained: there may be another trigger mechanism of 1 for gastric diseases. There are 1 endogenous substances in human body, of which 1 is similar to nicotine, which I will call nicotine analog for the time being, and 1 is similar to one of the bitter herbs, which is called bitter herbs active substances. In general, the two neutralize each other; If the content of nicotine analogues is high, it will cause stomach problems.

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