With the development of medical science and technology and the promotion of medical and health system reform in China, the development focus of hospital pharmacy has changed under the new situation. The following is what I collected for you. Welcome to read the reference!

1 On the present situation and development suggestions of biopharmaceutical industry in China.

With the rapid development of science and technology in China, biotechnology is the main force of high-tech in 2 1 century. As a new industry, its development prospect is very broad. After years of research and innovation, China's biopharmaceutical technology has made some achievements, but there are still some obstacles that need to be solved in time. This paper briefly analyzes the present situation of biopharmaceutical industry in China, and puts forward some reasonable suggestions.

Biopharmaceuticals; Current situation; develop

The research and development of biopharmaceuticals are based on modern engineering, such as genetic engineering, protein engineering, antibody engineering and cell engineering. The basic principle of biopharmaceuticals is to recombine microbial DNA, so as to improve medicinal properties and nutritional value and reduce side effects. Biopharmaceutical is a synthesis of biology, medicine and pharmacy. The biopharmaceutical industry has the characteristics of high investment, high risk and high return, which leads to a high threshold for the industry. To promote the progress of China's pharmaceutical industry, we must fully understand its development status and problems, so as to continuously optimize the industrial structure and pharmaceutical technology.

First, the development status of biopharmaceutical industry

According to Professor Tan Shuhua of China Pharmaceutical University, the United States accounts for 63% of global biotech drugs, Europe accounts for 25% and Japan accounts for 7%. With the continuous development of biopharmaceutical technology, the market share of biotechnological drugs in the pharmaceutical industry is increasing, and China's biopharmaceutical industry is paying more and more attention to the research and development of biopharmaceutical technology.

Biopharmaceutical technology is a high-tech emerging industry. After decades of efforts, China's biopharmaceutical technology research and development has made some achievements in interferon, vaccine, growth factor and other aspects, and has been applied to the production of biopharmaceutical industry, and at the same time, it has also made some achievements in the research of drugs such as tumors and cardiovascular diseases. China should clearly realize that biopharmaceutical technology is in the primary development stage. With China's strong support for biotechnology, biopharmaceutical technology in China will continue to develop. In the next 5 ~ 10 years, more than 20 biopharmaceutical drugs in China will be approved by SFDA, and some of them will enter the international market, forming a biopharmaceutical industry production chain with cloned antibodies as the core, increasing China's influence in global biopharmaceutical research and development, shortening and promoting it.

Second, the problems existing in the development of biopharmaceutical industry in China

Although China's biopharmaceutical industry has made some achievements in recent decades and has great development potential, there are some loopholes in its production chain because of its immature development and exhibition, which hinders the better and faster development of China's biopharmaceutical industry. First, the development of biopharmaceutical technology in China is not yet mature, and the innovation ability of biotechnology drugs is weak; Second, the market investment is not optimistic. The market investment of new biotechnological drugs developed in China is not smooth, and there are fewer ingredients in global biotechnological drugs. Third, China's medical technology research and development is out of touch with the international community; Fourth, the production structure of biopharmaceuticals is unreasonable.

Three. Suggestions on the development of biopharmaceutical industry in China

China's biopharmaceutical technology will bring great changes to China's agriculture, medical care and other industries in the next few decades, provide a broad market space for the biopharmaceutical industry, and gradually improve the influence of China's biopharmaceutical industry in the global market.

1. Optimize the production mode

The development of medicine in China has a long history, which provides rich drug resources for the biopharmaceutical industry in China. The curative effect of traditional Chinese medicine has great influence in the world, which has laid the foundation for China biopharmaceutical industry to enter the international market. China's biopharmaceutical industry is facing the rapid development of global biopharmaceutical technology, so it is necessary to establish its own unique biopharmaceutical industry management model. For example, in the production mode of Chinese herbal medicine, the natural and pollution-free pure plant medicine resources are used to study the technology of fermentation, enzymatic extraction and other effective components, and modern biotechnology is applied to related industries to expand the market scale of China's characteristic biopharmaceutical industry.

2. The development trend of industrialization

With the development of biopharmaceutical industry in China, the research and development of new drugs will inevitably become the focus of its research and development. * * * and Chinese universities should strengthen the cultivation of biopharmaceutical technical talents, establish advanced biopharmaceutical R&D centers and posts for them, and combine their R&D centers with pharmaceutical enterprises to establish complementary relationships, which is conducive to the research and development and marketing of new drugs. Then, enterprises should join forces, establish technology and production alliances, learn from each other's strengths, give play to their respective advantages in their respective fields, obtain the highest profits at the lowest cost, and increase their respective competitive strength. For example, transferring high-tech biopharmaceutical technology R&D to small pharmaceutical enterprises with technical strength reduces the cost of new drug research and development and shortens the R&D cycle, thus accelerating the cycle of technology transforming productivity and promoting the industrialization of biopharmaceutical industry. Coupled with the strong support of the state, through macro-control means and financial, material and human support, it will inevitably accelerate the pace of development of China's biopharmaceutical industry.

3. Expand the market scale of biopharmaceutical industry.

The biopharmaceutical industry is a modern industry integrating biotechnology, medical technology and other technologies. Its development depends not only on the research and development of biotechnology, but also on the research and development of related technologies, such as new technologies such as information technology and image processing technology. The combination of computer simulation technology and biomolecular technology is beneficial to the research and development of new biotechnological drugs, and the simulation system can give full play to the effectiveness of new drugs and greatly reduce the cost of new drug research and development. Therefore, the combination of new technology and biotechnology is helpful to shorten the research and development cycle of new drugs in biopharmaceutical industry and improve their efficacy and safety. The combination of biotechnology and information technology has promoted the rapid development of biopharmaceutical industry.

4. Innovation and key breakthrough of R&D mode

The traditional research and development model of biotechnology drugs has fallen behind the times and is no longer suitable for the development of biopharmaceutical industry. Today's R&D mode has changed from the simple R&D mode of traditional paradigm synthesis and universal screening to the advanced R&D mode of targeted and focused screening, optimization and evaluation of lead compounds. Release drugs

With the continuous progress of biopharmaceutical technology in China in recent years, China's biopharmaceutical industry is gradually in line with the international biopharmaceutical market. In the next decade, China will focus on developing humanized therapeutic monoclonal antibodies, antisense drugs, gene therapy drugs, soluble protein engineering drugs, nucleic acid drugs, cell therapy and other fields. For example, research and development of new drugs with the help of protein engineering technology; Research and development of antisense oligonucleotide drugs: combine advanced genetic engineering technology to develop new drugs; Discover the research and development direction and resources of new drugs; According to the investigation, human antibody drugs account for 20% of the antibody drugs on the market at present, but clinical drug experiments account for 50%, so human antibody has great market development potential.

Conclusion:

To sum up, biopharmaceutical industry is a new industry in 2 1 century, with great development potential. With the technical progress in various related fields and the strong support of China, China's biopharmaceutical industry will surely make greater achievements. In the future development process, we should pay attention to the optimization and innovation of production mode and R&D mode, conform to the development trend of industrialization, expand the market space of biopharmaceutical industry and the key breakthrough of new drug research and development, establish a good living space for the development of biopharmaceutical industry in China, tap the development potential of biopharmaceutical industry, shorten the gap with biopharmaceutical technology in advanced countries, and strive to make China's biopharmaceutical industry in line with international standards and enhance its comprehensive strength.

References:

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[2] Yang. Development status and trend of biopharmaceutical industry in China [J]. Guangzhou Chemical Industry.2012 * * * 9 * * *

[3] Tao Ran, JUNG WOO. China biopharmaceutical industry status and development suggestions [J]. China Pharmacy.2012 * * * 37 * * *

[4] Sharla Cheung, Wang Yangdong and Jia Wei. Research on the development of small and medium-sized biopharmaceutical enterprises in China based on the information of innovation funds [J] China Science and Technology Forum.2014 * * * 7 * * *

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