A toothpaste manufacturer in Guangxi launched the activity of "using fluoride toothpaste carefully and refusing fluoride from the mouth" in Taiyuan, Shanxi, which recently attracted considerable attention. The local media article pointed out: "The harm of high fluoride has a long history, which is caused by people's long-term excessive intake of fluoride such as sodium fluoride and sodium monofluorophosphate, and its pathological process is relatively hidden. However, for a long time, the general public knew little about this situation and did not pay enough attention to it. Even many people still use fluoride toothpaste. " Related news also appeared "alert! The tragic skeletal fluorosis is by your side! " This exciting formulation. When this theory came out, the readers were in an uproar. In the articles led by these manufacturers, no matter how obscure and specious the articles themselves are, "fluoride toothpaste" and "fluorosis" are implicitly related, which is directly "fluoride toothpaste". Almost all consumers know the efficacy of fluoride toothpaste, which can not only inhibit dental plaque, but also protect enamel and enhance the acid resistance of teeth. It plays a very important role in preventing dental caries, especially for parents who give it to their children from an early age. Now that such an article comes out, no matter whether it is from a high-fluorine area or not, I am afraid there will be questions: Can this fluoride toothpaste still be used? The reporter interviewed the famous toothpaste manufacturer who initiated this activity by telephone. Mr. Li, director of the company's planning department, believes that fluoride can prevent dental caries, but it can also cause chronic fluorosis. So under what circumstances can fluoride toothpaste cause chronic fluorosis? Mr. Li believes that there are two aspects: first, the content of fluorine, because it is not easy to determine whether there is fluorine exceeding the standard in fluoride toothpaste on the market at present, so the possibility of fluorosis cannot be ruled out; Second, users think that children are particularly easy to swallow toothpaste when brushing their teeth, which leads to excessive fluoride intake. As for whether adults will suffer from fluorosis due to frequent use of fluoride toothpaste to brush their teeth, Mr. Li believes that "excessive intake will lead to fluorosis." But at the same time, he also stated: "At present, it is not clear how much intake is excessive." Since the slogan of "reducing fluoride intake and preventing fluorosis" has been put forward, has the enterprise made any relevant investigation on fluorosis caused by fluoride toothpaste? Is there any scientific research to support this view? When the reporter raised this question, Mr. Li said that the company had not done market research before, and there was no corresponding data on the harm of fluoride toothpaste. According to Mr. Li, enterprises produce and promote fluoride-free toothpaste "in the hope that through this activity, they will make a new inventory of the toothpaste industry and advocate the healthy fashion of using green fluoride-free toothpaste." Reducing fluoride intake and preventing fluorosis are our main goals. "I hope these brands, including Colgate and Crest, can also produce some fluoride-free toothpaste. This is good for consumers. " "Since the country allows the production of fluoride toothpaste, the countries with fluoride content have relevant regulations and standards. As long as this standard is met, fluoride toothpaste should be safe? In this regard, Mr. Li's answer is: "Although the state has standard control over the fluoride content of fluoride toothpaste, it does not rule out that some manufacturers will allow fluoride to exceed the standard for better toothpaste effect. "Fluoride toothpaste is not too much, but too little! Can fluoride toothpaste really cause chronic fluorosis? Bian Jinyou, a famous stomatologist in China and a professor at Peking University College of Stomatology, holds different views. " If fluoride toothpaste is not used properly, dental fluorosis may appear, but it will only appear in children with poor teeth development. For adults with well-developed teeth, this effect is impossible. There is absolutely no way to have skeletal fluorosis. "Professor Bian made it very clear." In the research process of more than half a century, the anti-caries effect of fluoride toothpaste has experienced more than 100 clinical experiments, which proved its positive effect and was recommended by the World Health Organization and the International Dental Union (FDI). The role of fluoride toothpaste in preventing dental caries is clear and internationally recognized. ""At present, fluoride toothpaste has been widely used in developed countries or countries with high incidence of dental caries, with a market share of more than 90%~95%, while it is rarely used in developing countries, with a small market share. The important reason is that the price of fluoride toothpaste is usually 2~3 times higher than that of ordinary toothpaste. Therefore, the World Health Organization has even developed a formula with lower cost and lower price for developing countries to promote the use of fluoride toothpaste in developing countries. "However, there are not many fluoridated toothpastes in the domestic market at present. Professor Bian Jinyou said that according to the survey of relevant institutions, the current usage ratio is about 30%~40%, and it is mainly concentrated in big cities such as Beijing and Shanghai. Professor Bian Jinyou introduced that the fluoride content of fluoride toothpaste has internationally recognized standards: the fluoride content of children's fluoride toothpaste is 500mg per kilogram, and the fluoride content of adult toothpaste is1000 mg ~1100 mg-which means the fluoride content of toothpaste per kilogram. The fluorine content in fluoride toothpaste is not as high as possible, but too little to prevent dental caries. When the fluoride content in fluoride toothpaste is higher than 500 mg, it will effectively prevent dental caries. When it exceeds 1 100 mg, the caries prevention effect will not increase, but there is a danger of poisoning. At present, China only stipulates the safe content of fluoride in fluoride toothpaste. Regardless of adults and children, the standard is that the fluoride content per kilogram of toothpaste is less than 1500 mg, but the effective fluoride content is not specified. It seems that the fluoride content of fluoride toothpaste in China seems to be relatively high, but in fact this 1500 mg is only an "upper limit". Professor Bian Jinyou introduced that according to the sampling results of fluoride toothpaste in Beijing market by relevant institutions in the past, the fluoride content of fluoride toothpaste in the market is actually very low, many of which are below 500 mg. Professor Bian Jinyou said that when toothpaste manufacturers produce fluoride toothpaste, the fluoride content may reach 500 mg, which is an effective dose to prevent dental caries. However, after the toothpaste leaves the factory, fluoride ions in it will soon combine with other ions to form new compounds, thus making the toothpaste lose its original function. Because there is no relevant monitoring organization at present, it is difficult to make an accurate evaluation of fluoride toothpaste products on the market. There may be three problems in product quality: insufficient fluorine content, unstable quality or excessive fluorine content. Professor Yang Shenghui from the Institute of Stomatology, Beijing Stomatological Hospital believes that the manufacturers have not conducted market research and have no relevant clinical data on a series of chronic fluorosis such as dental fluorosis and skeletal fluorosis caused by fluoride toothpaste. In this case, the promotion of fluoride toothpaste together with dental fluorosis and even skeletal fluorosis exaggerates the minimum negative impact that fluoride toothpaste may have if used improperly. For a country with a high incidence of dental caries in China, such publicity is obviously not conducive to the popularization of fluoride toothpaste, and has a certain misleading effect on the correct use of fluoride toothpaste to prevent dental caries. Professor Bian Jinyou pointed out: "There is nothing wrong with advocating the cautious use of fluoride toothpaste in high fluoride areas. The key point is that the negative effects of fluoride toothpaste cannot be infinitely amplified, which will affect the normal use of people in low fluoride areas. Caution does not mean prohibition, and people need not be overly nervous about it. Promoting the benefits of fluoride toothpaste is not advocating everyone to use it. In fact, even in countries where fluoride toothpaste is widely used, there are fluoride-free toothpastes. "Regarding the correct treatment and use of fluoride toothpaste, Professor Bian Jinyou put forward the following principles: use it with caution in high fluoride areas, especially children; Appropriate use in low fluorine areas. " Caution in high fluoride areas is not only to prevent excessive fluoride intake under improper use, but also to prevent toothpaste from increasing the fluoride content in local water and soil with sewage discharge. "Professor Bian Jinyou said. In short, it is necessary to "eliminate fluoride harm" in high fluoride areas and "promote fluoride benefit" in low fluoride areas. Small link: Don't squeeze your toothbrush when using toothpaste. Can squeeze out the size of "soybean" every time. Professor Bian Jin pointed out that improper use of fluoride toothpaste may cause poisoning, which mainly means that people ingest more fluoride when brushing their teeth, mainly in children: children before the age of 3 will swallow 50% toothpaste by mistake; 3-9 years old children swallow about 25%; The other population is 5%~ 10%. In view of the correct use of fluoride toothpaste, there is no warning or explanation for the products on the market at present. Professor Bian Jinyou suggested that children before the age of 3 should not advocate the use of fluoride toothpaste. Children aged 3~6 should be used under the guidance of teachers or parents. When using fluoride toothpaste, it should be controlled at 1~2 times a day, and the amount of toothpaste used each time is about the size of a soybean, instead of squeezing a toothbrush like TV commercials. In addition, fluoride toothpaste can be recommended to the following people: people with dental caries tendency, especially children, elderly people with dental caries or dental caries, and some special people, such as people whose salivary glands are destroyed after radiotherapy. Because the fluoride content in fluoride toothpaste will be lost over time, the validity period of fluoride toothpaste abroad is usually 2 years. At present, there are no relevant regulations in China, so Professor Bian Jinyou suggested that when people use fluoride toothpaste, it is best to use it within two years from the date when toothpaste leaves the factory.

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