It depends on the specific types of karst landforms. Usually, karst landform (limestone landform) has little to do with biological activities, but it is not absolutely irrelevant. Especially in caves, the formation of many karst micro-landforms is related to biological (especially microbial) activities. As far as I know, Chea Chang is engaged in the research on the influence of biological activities on karst landforms in China, and relevant papers can be found.

Progress in Earth Science >> 1995 10 Volume 5 > > Study on Biokarst and Its Micro-morphology

Microscopic morphology of algae in karst erosion, Acta Geographica 1993, Vol.48, No.3.

Journal of Geography, 1993 Preliminary study on karst erosion of lichens.

All these documents show that the formation of karst landforms is related to biological activities.