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What is the pharmacology and toxicology of Jiekou Bi Ke Pill?
Hello, pharmacological action of Radix Angelicae Pubescentis in Jiekou Kebi Pill: 1. Spasmodic effect: Ecological citronellol, xanthotoxin and isoimperatorin in Radix Angelicae Pubescentis have obvious spasmolytic effect on rabbit ileum.

2. Analgesic, sedative and anti-inflammatory effects: intraperitoneal injection of Duhuo decoction 2g/kg can obviously prolong the animal pain reaction time caused by hot plate method in mice, indicating that Duhuo decoction has obvious analgesic effect. The liquid extracts of Radix Angelicae Pubescentis and Radix Angelicae Pubescentis decoction of mice or rats were given by gavage or subcutaneous injection, and the animal appearance showed a state of sedation and hypnosis. Subcutaneous injection of Radix Angelicae Pubescentis can also prevent convulsion caused by strychnine, but the frog eventually dies.