The sulfonyl compound in omeprazole is omeprazole sulfone, also known as omeprazole impurity A, which belongs to sulfoxide compounds. Sulfonyl compounds have been widely used to treat peptic ulcer related diseases caused by excessive gastric acid secretion because of their activities of inhibiting H+ and treat enzyme (also known as proton pump) and effectively inhibiting gastric acid secretion. The molecules of these compounds have the structure of 2-[(2- pyridyl) methyl] sulfinyl ]- 1H- benzimidazole or the sulfoxide structure related to the structure. The sulfoxide of omeprazole sulfone refers to the general name of the compound formed by the combination of sulfinyl and hydrocarbyl R, and the sulfoxide compounds have strong polarity and strong oxidation. Sulfoxide compounds can have optical properties.

Activities. It is a solid at low temperature and is usually soluble in water, ethanol and ether. It can be reduced to sulfide by reducing agent, oxidized to sulfone by oxidant, and can also form salt with nitric acid. Can be made of sulfur.

Ether oxidation or Fourier-Kraft reaction of aromatic hydrocarbons and thionyl chloride. Adverse reactions Generally, we can look at the adverse reactions of omeprazole because they are very similar in structure.