Current location - Education and Training Encyclopedia - Graduation thesis - Wang Yue's Education and Scientific Research
Wang Yue's Education and Scientific Research
Research direction: mainly engaged in the study of immune molecular mechanism of tumor, using biochemistry, cell biology and mouse model to explore the tumor microenvironment mechanism that may involve related signal pathways in the malignant transformation of macrophages. Scientific research project: project leader: 1. National Natural Science Foundation of China: Mechanism of M-CSF and nuclear factor kappaB up-regulating Fra- 1 promoting the transformation of macrophages into M2d type in tumor microenvironment (starting and ending time: 2012/1-201512) 2. Tianjin Natural Science Foundation: Effect of STAT4 silencing on protein secretion of tumor cells (starting and ending time: 2009/4-20 12/3) 3. Study abroad fund project of the Ministry of Education. Nankai University's innovative research project: Inhibition of tumor JAK/Study on the effect of STAT4 molecules on tumor immunity through STAT pathway in vitro. Published China journal papers (* correspondent) Bird and Wang Yue * Research progress of tumor-associated macrophages in tumor treatment; Expression and correlation of Ezrin pAkt in lung cancer, International Journal of Immunology, Pan, Wang Yue, Jiang Zhansheng, Xie Guangru, Liu Dongge, Sun, Liu Birong; China Cancer Clinical Research Center Sun Lei, Wei Xiaoli, Zheng Huilin, Wang Qingshan, Xiang Rong and Wang Yue * studied the effect of silencing STAT4 and SOCS3 on helper T cell differentiation. China Journal of Medicine, Ni Hong, Wei Xiaoli, Li, Wang Yue * IL-6 induces M 1 macrophages to transform into tumor-related M2 macrophages. The medical journals of the People's Liberation Army Wei Xiaoli, Betty Wong * Tumor protein Histology Technology and Its Application, Basic Medicine and Clinic, Wei Xiaoli, Betty Wong * STAT4' s Mechanism of Action and Related Research In the Cell and Molecular Immunology of Diseases Betty Wong, Li,,,,,,, Yang Rongcun's inhibition of tumor JAK/STAT pathway in vitro to explore the effect of STAT4 on tumor immunity. Foreign medical information Wang Yuechang chromosome recessive inheritance agammaglobulinemia foreign medical teaching course 1. Theory of medical immunology (7-year clinical medicine, 3-year master) II. Honors and awards of medical immunology experiment (7-year clinical medicine, 3-year master) 1. In 2007, he directed the fourth undergraduate innovation research of Nankai University "100 Project" 2. In 2009, the "100 Project", which directed the sixth undergraduate innovative research in Nankai University, won the third prize. 3. In 2008, Nankai University won the first prize in the Young Teachers' Teaching Basic Skills Competition.