1928 British bacteriologist Fleming first discovered the world's first antibiotic-penicillin, and alexander fleming discovered penicillin by a lucky mistake.
1938, the German chemist Ernst Boris ernst boris chain saw Fleming's paper in an old book, and began to do purification experiments. ?
/kloc-in the winter of 0/940, Ernst Boris ernst boris chain extracted a little penicillin, which was a major breakthrough, but it was still far from clinical application.
194 1 year, the baton of penicillin purification was passed to Australian pathologist Walter Flory. With the assistance of the U.S. military, Flory isolated strains from the soil brought back by pilots from airports around the world when they went out to perform tasks, which increased the output of penicillin from 2 units per cubic centimeter to 40 units. ?
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1950 In March, Shanghai Penicillin Laboratory was established and began to develop and produce penicillin. 195 1 April, the first penicillin injection in China was successfully trial-produced. This invention ended the history that China could not produce antibiotics.
1953 In May, Shanghai Penicillin Laboratory was renamed Shanghai No.3 Pharmaceutical Factory, which was the first professional antibiotic production factory designed by China. In order to mass produce penicillin, Shanghai No.3 Pharmaceutical Factory used cottonseed cake powder instead of corn syrup and glucose instead of lactose, which solved the problem of bacterial pollution control in the industrial production of antibiotics.
1On July 28th, 953, the first industrial production of antibiotic penicillin in China was finally realized, thus ending China's long-term dependence on imported penicillin.
Baidu encyclopedia-penicillin