2. Since the forty-fourth year of Jiajing (1565), Li Shizhen has successively visited Wudang Mountain, Lushan Mountain, Maoshan Mountain, Niushou Mountain, Huguang, Nanzhili, Henan, Beizhili and other places to collect drug specimens and prescriptions, and consulted 925 medical books of past dynasties with fishermen, woodcutters, farmers, rickshaws, medical workers and snake catchers as teachers. Sanyi manuscript, in the 18th year of Wanli in Ming Dynasty (1590), completed the masterpiece Compendium of Materia Medica 1.92 million words. In addition, he also studied pulse science and eight strange meridians. There are many works, such as Eight Veins in the Strange Classics and Hu Ling Veins. He was honored as a "medicine saint" by later generations.
3. Compendium of Materia Medica Li Shizhen borrowed the name of Zhu's Compendium of Tongjian and named it Compendium of Materia Medica. It was compiled in the thirty-first year of Jiajing (1552) and completed in the sixth year of Wanli in the Ming Dynasty (1578), which lasted for 27 years. Due to the long editing time and huge scale, Naifu Naizi and disciple Pang Lumen wrote the outline of the book, and the second son Jian Yuan painted the book, which can be described as a collective work dominated by Li Shizhen.
4. Pulse Diagnosis on the Lake Li Shizhen felt that there were many shortcomings or even fallacies in the pulse science of traditional Chinese medicine at that time, so he compiled Pulse Diagnosis on the Lake on 1564 (forty-three years of Ming Jiajing) according to his father Li Yuechi's Inventing Four Diagnoses and other pulse theory in history.
5. Textual research on the Eight Veins of Strange Classics, written in 1577, 1 volume. This book makes textual research on the documents of past dynasties, and gives a detailed explanation of strange classics and main diseases, with opinions attached.