1983.09- 1987.07, majoring in chemistry, Sichuan University.
1987.09- 1993.03, majoring in organic science, Department of Chemistry, Sichuan University.
1993.04- 1994.09: Lecturer, Chemistry Department, Sichuan University.
1994.10-1999.06: Associate Professor, Department of Chemistry, Sichuan University.
1998.04-200 1.03: Associate researcher, Academician Zhi Zhiming, Department of Chemistry, Hong Kong University.
1 999.07-Up to now: Professor and Doctoral Supervisor, School of Chemistry, Sichuan University1,Chemical Biology (Biomaterial Chemistry)
2. Organic Chemistry (bioorganic chemistry)
3. Green chemistry (green synthesis methodology) (1). Zhang Qingfang, Yi, Wang Weijie, Wang, Zhang, Li Jianfeng, Ren, Chen Qingming, Guo, et al. Linear polycation ring-opening polymerization as a non-viral gene delivery carrier, biomaterials, 20 13, 34,5391-5401.
(2) Xie Zhengbo, Wang, Li, Zhou, Li, Wan, He, Tian, Le, Zhu Zhengguo, Yu, Xu Zhengqiang, Water-promoted stereoselective cross aldol condensation catalyzed by lipase, Chemical Abstracts, 2013,5,1935–/kloc.
(3) Du Jun, Huang, Zhou, Yu, Xu Qingqi, Pu, Li, Crown Ether-Tripyridine-Zinc (Ⅱ) sensor for highly selective fluorescence recognition of histidine, chemistry. Commun。 , 20 13, 49, 5399 - 540 1.
(4). Chen W., Tay, J.-H. Ying, J., Sabat, M., Yu, X.-Q.*, Pu, L.*, and the spirotricycles of mangiferol A were rapidly obtained by rhodium (I)-catalyzed pau son-Khand/[4+2] cycloaddition. Commun。 , 20 13, 49, 170- 172.
(5). Feng Jun, Yang, Zhang Xiaobo, Liang, Zhang, Yu Jianfeng, Zhang Xiaoqi, an EF? Efficient oxidative coupling method for synthesis of new diastereomeric biaryl diols from estrone and tetrahedralite. 20 13, 54, 355–357.
(6). Xie Zhibin, Wang, Ni *, Jiang Guangfeng, Yu, Xu Qiqing *, biocatalytic asymmetric aldol condensation in buffer solution, tetrahedron.2013, 54,945–948.
(7). He, Li, Li, Wu, Wang, Wang, water-promoted enantioselective aldol condensation of proline-cholesterol and-diosgenin, tetrahedron, 20 13, 69, 5 136-5 143.
Hou Junmai, Li, Guo Jianli, Liu Bingyuan, Liao Yaoxiang, Yu Xiaoqin, Liu Jianqing. Rst ratio probe for lysine in water, tetrahedron, 2013,69,2118-2123.
Hou Juntang, Li. K.*, Yu, K.-K., Wu, M.-Y, Yu, X.-Q.*, coumarin–DPA–Cu (II) as chemical sensing ensemble for the determination of histidine in urine and serum, Org. biomolecules. Chemistry. , 20 13, 1 1, 7 17-720.
(10). Xun mingmin, Zhang Xiaochun, Zhang, Jiang, yi Wenjun, Zhu Wenjun, Yu, Zhang Xiaochun, low molecular weight PEI-based biodegradable polymer as gene delivery carrier, tissue. Biomolecules. Chemistry. , 20 13, 1 1, 1242– 1250.
(1 1). Tao Fuyou, Wang Chunguang, Ma, Jin Guiying, Li, Tan Lilin, Zhang, Dai, Yu, Yu, Xu Qingqing, Synthesis of protoporphyrin derivatives and its application in reducing nitrosamine content in tobacco, Porphyrin Phthalocyanine Journal 20 13,/kloc-.
(12). Zhou Lihong, Wang, Chen Ning *, Zhang, Wei, Xie, Zhang Zhenbo, Yu Xiaoqing *, Catalytic Heterogeneity of α-amylase: Synthesis of 3- substituted chromene derivatives by biocatalytic domino oxygen-Michael/hydroxyaldehyde condensation reaction, Molecular Journal. Qatar. B: Enzyme. , 20 13, 9 1, 37–43.
(13). Lu Qingsheng, Hou Jiantao, Wang, Xu Baoying, Zhang, Li Jianli, Yu, Xu Jianqin, Recognition of Multichannel Chromogenic Anions and Chiral Anions by Imidazole Functionalized Binaphthol Derivatives, China. Doctor of chemistry. 20 13, 3 1, 64 1-650.
(14). Zhou Yanjun, Hu Chunlin, Wang, Zhang Wenwei, Yu, Xu Qingquan, Puri? Porcine pancreatic lipase cation in aqueous two-phase system of polyethylene glycol and potassium phosphate, Journal of Chromatography B, 20 13, 926, 77–82.
(15). Asymmetric catalytic alkyne addition reaction of Chen, Wei, Tai, Ying, Yu, Chen, Pu, Li and aldehyde dyes and rhodium (Ⅰ)-catalyzed stereoselective domino effect? Khand/[4+2] cyclic addition, j.org. Chemistry. 20 13, 78, 2256 – 2265.
(16). Li, Wang, Xu, Hu Hairui, Yu, Wang, Hou, Yu Jiantao, Yu Xiaoqing *, a probe for hydrazine color ratio based on coumarin, analysis. Methods: 2013,5,2653-2656.
(17). Liu, Jiang, Zhang qingquan, yi, Wang Weijie, Zhang jinxia, Zhang Xiaochun, Wu mingbo, Zhang Yuming, Zhu Wenming, Yu, Zhang qingquan, synthesis of novel imidazole-functionalized naphthenic cationic lipids and their application as non-viral gene vectors. Medicine. Chemistry. 20 13, 2 1, 3 105–3 1 13.
(18). Wu Meiyan, He, Tian, Li, Huang, Wu, Huang, Yu, Xu Qingqiu, Real-time colorimetric and ratio system? Sul's fluorescent probe Te, analyst, 20 13, 138, 3018–3025.
(19). Xu Hairui, Li, Jin Keli, Liu, Zhang, Wu, Wang Tianming, Wang Mingqing, Hou Juntang, Huang, Zhang, Xie, Yang Mingming, Yu, Xu Jinqing, anthracene-naphthene conjugate: rst and other equivalent responses? Fluorescent chemical sensor for Pb2+ in aqueous solution, analyst, 20 13, 138, 2329–2334.
(20). Jiao Shiyou, Peng, Liu Lilin, Li, Wang Keli, Xie, Wang Yongming, Ao Mingzhong, Wang, Yu and Xu Qiqing, a ratio fluorescence sensor based on binaphthol, used to selectively identify histidine in aqueous solution, analysis, 20 13,138,5766.
(2 1). Xie Zhibin, Wang, N.*, Wu, m-y, He, T, Le, z-g, Yu, x-q. *, Grinding Method for Catalyst-free and Solvent-free Michael Addition of 1, 3- dicarbonyl compounds with nitroolefins, Beilst. , 20 12, 8, 534–538.
(22). Huang, Zheng, Du, Zhang, Zhang, Yu, Xu Qiqing, Pu, Li, high selectivity? Fluorescence identification of Zn2+ in water with tripyridine-copper chloride and analysis. Methods: 2012,4, 1909- 19 12.
(23). Metal-free oxidative esterification of Feng Jun, Liang, Chen, Zhang Shiying, Fu Shisheng, Yu, Xu Qingquan and benzyl with carbon-hydrogen bonds, advanced synthesis. Qatar. , 20 12, 354, 1287- 1292.
(24). Zhang Wenwei, Wang, Zhou Yongjie, He Tiantao, Yu Xiaoqi, Improvement of lipase activity and stability by microemulsion organic gel immobilization and its application in the synthesis of aryl ethyl acetate, molecule. Qatar. B: Enzymatic, 2012,78,65–71.
(25). Li Shusheng, Wang, Yang, Wang Shusheng, Zhang, Wu Shifang, Wang Baolin, Zhu Wenlin, Yu, Xu Qingqing, biodegradable linear and crosslinked polymers as non-viral gene carriers, bioengineering. Medicine. Chemistry. , 20 12, 20, 1380– 1387.
(26). Huang Qide, Ren, Ren, Ou, Wang Weijie, Fu Yuying, Cai Mingqi, Zhang, Zhu Jianli, Zhu Wenli, Yu, Xu Jianqi, cationic lipids containing benzene rings and ammonium groups as gene delivery carriers, chemistry. biology Drug design. , 20 12, 79, 879-887.
(27). Wu Meiyan, Li, K*, Hou Juntang, Huang, Zhong, Yu, Xu Qingqin *, A Selective Colorimetry and Ratio Measurement? Hydrogen sulfide fluorescent probe? de，Org。 Biomolecules. Chemistry. , 20 12, 10, 8342-8347.
[4+1] enantioselective cycloaddition of allyl acetate with CO catalyzed by [rhcl (co) 2] 2. Chemistry. , 20 12, 77, 62 15? 6222.
(29). Identification of copper ions and sulfur ions by Wang Mingqing, Li, Jin Keli, Hou Juntao, Wu Mingyou, Huang, Zhou, Yu, Jin Keli and Binaphthol-based fluorescence sensor? Anions in water. Chemistry. , 20 12, 77, 8350? 8354.
(30). Direct arylation of aromatic hydrocarbons and azaaromatic hydrocarbons by Wen, Zhang, Chen, Yu, Zhang, Yu and diaryl iodonium salts. Chemistry. , 20 12, 77, 766-77 1.
(3 1). Huang qingde, Ren, Chen, Hou, Ou, Wang Weijie, Zhang, Zhu, Fu, Yu, Yu, Xu Qingqing, et al., Cycloalkenyl cationic lipid with carbamate bond as high efficiency and low toxicity gene delivery carrier, ChemPlusChem, 20 12, 77.
Huang, Zheng, Du, Zhang, Zhang, Yu, Xu Qingqi, Li, A Jian and E? Ancient? Histidine chemiluminescence sensor. Commun。 , 20 12, 48, 34 12-34 14.
(33). Wang Jun, Wang, Wang, Zhang, Yu, iron-mediated direct arylation of arylboronic acid, chemistry. Commun。 , 20 12, 48, 1 1769– 1 177 1.
(34). Zhang, Yang, Huang, Yang, Zhang, Zhang, Zhang Dewei, Liu, Lin, Lin Haihong, Yu, Xu Haiqing, et al., Synthesis of copper (Ⅱ) complex of PNA-cyclen conjugate, DNA binding and cleavage study, Sci. China chemical industry. , 20 1 1, 54( 1), 129- 136.
(35). Zhang, Yang, Wang, Zhang Meiqi, Zhang Dewei, Lin, Hu Haihong, Yu, Xu Meiqi, synthesis of novel PNA-Cyclen complex, DNA binding and cleavage research, chemistry. Biological diver. , 20 1 1, 8, 827-840.
(36). Huang, Zheng, Chen, Chen, Zhang Jun, Yu, Chen, Li, Binbinaphthol and Tripyridine: electronic effect of bond, tetrahedron., 2011,52, 5497–5500.
Wu Minying, Wang Minqi, Li, Wang Keli, Feng Xiaowei, He, Tian, Wang, Ni, Yu, Xu Xiaoqi. An efficient and transition metal-free method for the synthesis of substituted dihydrofuran by Michael/cyclization series reaction, Tetrahedral Lite. 20 1 1, 52, 679–683.
(38). Wu Mingyu, Li, Li Ke *, He, Tian, Feng, Wang Xiaowei, Wang, Wang Xiaoyun, Yu, Chen Xiaoqing, a new enzyme tandem process: synthesis of 5- hydroxyimino-4,5-dihydrofuran, tetrahedron, 201/kloc-with high stereoselectivity by biocatalysis.
(39). Du, X, Wang, Q.*, He, X, Peng, R.-G, Zhang, X, Yu, X.-Q.*, Highly enantioselective addition of linear alkyl alkynes to aromatic aldehydes, tetrahedron: asymmetric, 201,.
(40). Hou Juntao, Bingo Chang, Xu Baoying, Lu Qingsheng, Liu Qingqiu, Zhang Junjie, Yu, Xu Qingqiu, click chemical synthesis of a novel diol-based cyclophane and its application in silver ion sensing, tetrahedron. , 20 1 1, 52, 4927–4930.
(4 1). Ye, Yang Honghui, Zhang, Wang, Chen, Chen Shiying, Yu Xiaoqing, cobalt-catalyzed dehydrogenation coupling amination of benzyl cyclohexylmethane, tetrahedron, 20 1 1, 67, 4649-4654.
(42). Wang Mingqing, Zhang Meijuan, Zhang Yuying, Zhang Dewei, Liu Qingqiu, Liu Jianlin, Lin, Yu Haihong, Yu, Zhang Qiuqing, Metal-free DNA cleavage efficiency and biological reaction kinetics of a novel PNA analog bridged macrocyclic polyamine. Medicine. Chemistry. Ritter. , 20 1 1, 2 1, 5866-5869.
(43). Yi Wenjun, Feng, Zhang Zhenfeng, Zhang Jianfeng, Li, Li Liangde, Zhu Wenlin, Yu, Xu Jianqing, Preparation of glycol glycidyl ether bridged ring compounds and their application in gene transfer. Biomolecules. Chemistry. , 20 1 1, 9, 24 13-242 1.
(44). Li Shusheng, Wang, Yang, Zhang, Li Junfeng, Yang Weihong, Dai, Zhu Zhenhong, Zhu Weihong, Yu, Xu Qingqing, biodegradable cross-linked polyurethane gene carrier material, PEI, Mol. Biologist. , 20 1 1, 7, 1254- 1262.
(45). Wu Mingyu, Li, Wang, He, Yu, Xu Qingquan, A new catalyst-free series reaction for the synthesis of 5- hydroxy-1, 5- dihydro -2H- pyrrole -2- one in water medium, synthesis, 201,/kloc-0.
(46). Wang Haiyan, Zhou Yujun, Wang, Li, Yu, Li Chunqing, enzymatic synthesis of a novel heat-sensitive polyester containing ketoprofen macromolecules. Biosci。 , 20 1 1, 1 1, 595–599.
Huang Qide, Ou, Wang Weijun, Chen, Wang, Wang Zhenjun, Zhang, Zhu Weijun, Yu, Zhang Weijun, et al., Application of novel cationic lipid protonated ring and imidazole salt in gene therapy. J. Pharm。 Biopharmaceutical. , 20 1 1, 78, 326–335.
(48). Huang qingde, Zhong, Guo Guangxiang, Zhang, Yang, Ren Jun, Fu, Yang, Zhang, Zhu, Yu, Xie Guangqing, Cyclone-based cationic lipids for efficient gene delivery in tumor cells, PLoS ONE, 201,6, E23/kloc-. doi: 10. 137 1/journal . pone
Liu Jianlin, Ma, Qin Ping, Huang, Zhang Qingde, Yang Wenhui, Zhang, Wang Jianyou, Zhu Wenwei, Yu, Xu Qingqing, Cationic Lipids with Protonated Ring and Different Hydrophobic Groups: Synthesis and Application of Gene Transfer System, Europe. Doctor of medicine. Chemistry. , 20 1 1, 46, 4 133-4 14 1.
(50). Wang Mingqing, Liu, Liu Jianlin, Wang Jianyou, Zhang, Zhang Dewei, Zhang, Tang, Lin, Lin Haihong, Liu Yuying, Zhao Yufeng, Yu, Xu Jianqing, Site-selective DNA hydrolysis induced by metallopeptide-free nucleic acid-cyclase conjugate, chemistry. Commun。 , 20 1 1, 47, 1 1059- 1 106 1.
(5 1). Wang Jun, Hou Juntao, Wen, Zhang, Yu jianqing, iron-catalyzed direct amination of azametallocene compounds, chemistry. Commun。 , 20 1 1, 47, 3652-3654.
(52). Zhang Qingfang, Yang Wenhui, Yi, Wang Wenjun, Zhang, Luo Jianli, Ren, Luo Tianying, Zhu, Wang Wenli, Yu, Preparation of Cationic Lipid with Ester Bond and Its Application in Gene Vector. Medicine. Chemistry. Ritter. , 20 1 1, 2 1, 7045–7049.
(53). Wen, Chen Xiaoyan, Fu Xiaoyan, Zhang, Chen Xiaoyan, Chen Xiaoyan, Yu, Chen Xiaoqin, A Jian and EF? Efficient synthesis of pyrazole in water, tetrahedron, 20 1 1, 67,9618-9621.
(54). Lu Qingsheng, Zhang Jun, Jiang, Lu, Hou Jiantao, Yu, Xu Qingqiang *. Fluorine ion based on glycol imidazole cyclophane with double channels and tetrahedral lites. , 20 10, 5 1, 4395–4399.
(55). Feng Xinwei, Wang, Zhang, Yang, Wang, Yu, Copper-catalyzed Nitrogen Loss of Sulfonyl Hydrazone Compounds: Reduction Strategy for Sulfone Synthesis from Carbonyl Compounds. Ritter. , 20 10, 12, 4408-44 1 1.
(56). Turlington, M., Yue, Y., Yu, X.-Q.*, Pu, L.*, Catalytic asymmetric synthesis of chiral propargyl alcohol for intramolecular Pauson-Khand cycloaddition, J.org. Chemistry. , 20 10, 75, 694 1–6952.
(57). Wang, Li, Chen, Li, Chen, Chen, Yu, Chen -Q, Enzymatic Domino Synthesis of 2- alkylbenzimidazole in Solvent-free System: A Green Synthesis Route of Heterocyclic Compounds. B: Enzyme. , 20 10, 67, 16–20.
(58). He Tietao, Li, Jin Keli, Wu Mingyu, Feng, Wang Xiaowei, Wang, Wang Haiyan, Li Chunchun, Yu, Xiaoqi Chen, direct Mannich reaction by biocatalytic hybridization, molecular chinese journal of catalysis. B: Enzyme. , 20 10, 67, 189– 194.
(59). Qin Jun, Meng, Chen Xiaowei, Li, Li Bingjun, Ha, Wei, Yu, Zhang Xiaoqing, Zhang, et al., Self-assembly of β -cyclodextrin and Planck into hollow nanospheres in aqueous solution, colloidal interface science. , 20 10, 350, 447–452.
(60). Li, Chen, Zhou, Yang, Wang, Feng, Li, Yu, Yang, Li, Yang, Li, etc., Journal of Biotechnology, 20 10,150,539-545.
(6 1). Liu, Jasmine Zhang, Zhang, Wang, Zhang Mingqing, Zhang Dewei, Lu, Huang Qingsheng, Lin, Hu Haihong, Yu, Zhang Qingqing, Synthesis, DNA binding and cleavage activity of macrocyclic polyamines containing mono-or bis-acridine groups. Doctor of medicine. Chemistry. , 20 10, 45, 5302-5308.
(62). Wang Haiyan, Zhang Wenwei, Wang, Li, * Li, Li, Yu, Xu Qingquan *, Biocatalytic synthesis and in vitro release of linear polyester containing ketoprofen biomacromolecules, 20 10,1,3290–3293.
(63). Chen, Chen, Huang, Chen, Li Shuying, Li, Yu, Xu Qingqi, Pu, Li, Enantioselective gel folding: a new visual chiral sensing method. Chemistry. Socialists, 2010,132,7297–7299.
(64). Wen Jun, Qin, Ma, Lin Lifeng, Dong, Lin, Zhang Jun, Liu, Duan, Yang Shengsheng, Chen Shengying, Hu Chunwei, Yu, Xu Qingquan, Iron-mediated Direct-Gongpu Reaction: A New Method of Ortho-arylation of Pyrrole and Pyridine, Organic. Ritter. , 20 10, 12, 2694-2697.
Item (65), Feng Zhihong, Zhang, Liao Yulian, Yu Chunjun, Yi, Wang Weijun, Zhu Wenxia, Yu Xiaoqing, Application of linear cyclic olefin polyamines in gene transfer. Biomolecules. Chemistry. , 20 10, 8, 640–647.
(66). Synthesis of methyl propiolate, Chen, Chen, Wang, Yu, Huang, Huang, Pu, Li, C 1 Symmetric Bibipyridine Ligands and Addition Reaction of Aromatic Aldehydes with High Enantioselectivity, Tetrahedron, 20 10/0,66,1990-
(67). Chen, Chen, Liu, Liu, Sun Haibo, Yu, Chen, Li, Bibipyridine multi-task catalyst for sequential oxidation and asymmetric alkylation of alcohols, tetrahedron. , 20 10, 5 1, 2345–2347.
(68). Huang, Yang, Liu, Liu Jilin, Zhang, Liu, Hou, Zhang Jitao, Zhang, Zhang Dewei, Lu, Chen Qingsheng, Chen, Lin, Hu Haihong, Yu, Xu Qingqing, Interaction between diaryl functionalized molecules and nucleosides and nucleic acids, Sci. China chemical industry. , 20 10, 53, 103– 1 12.
(69). Zhou Lihong, Yu, Xu Jianqing, Pu, Li Lihong, Reactivity of dimers of propiolic acid with nucleophiles and effective synthesis of dimethyl α-aminoadipate, tetrahedron. , 20 10, 5 1, 425–427.
(70). Zhou Lihong, Yu, Xu Qingqi, Pu, Li Lixia, sodium promoted alcohol oxidation to ketone, tetrahedron. , 20 10, 5 1, 475–477.
(7 1). Meng Xiaowei, Qin, Liu, Yang, Fan, Mi-Mi, Li, Zhang Baojun, Zhang, Yu Xiaoqing, biodegradable hollow spheres based on self-assembly inclusion, chemistry. Commun。 , 20 10, 46, 643–645.
(72). Liu Peiying, Li, Wang Gang, Zhang Jun, Zhang Dawei, Lin, Hu Haihong, Yu and Wang Xiaoqi, who is the king? A- hydroxy -B- oxo -a, B- ketene moiety or catechol b ring: the relationship between the structure of quercetin derivatives and their ability to promote oxidation, chemistry Biological diver. , 20 10, 7, 236-244.