Union Medical College Hospital is one of the earliest hospitals in China to carry out renal biopsy, and he is the main person in charge of this work. Renal biopsy is of great significance for the diagnosis and treatment of renal diseases. Since percutaneous renal biopsy was carried out in 198 1, nearly 10,000 cases of renal biopsy have been carried out, with a success rate of over 95%. Over the years, renal biopsy technology has been used to guide clinical work, determine the treatment plan according to pathological types, and improve the cure rate. Carry out immunofluorescence technology and ultrastructural research on renal diseases, and establish and improve laboratory work. To study the ultrastructure of IgA nephropathy and compare the argument that IgA nephropathy and henoch-schonlein purpura nephritis are the same clinicopathological entity. In the study of lupus nephritis, the special manifestations of SLE immunofluorescence were found, and the basis for early diagnosis of subclinical lupus nephritis was put forward.

He has a rigorous academic attitude, pays attention to training young doctors, sets an example and serves as a national senior nephrologist class. He teaches students of Union Medical College every year and is a master tutor.

65438-0988 participated in the national natural fund research project "Study on the pathogenesis of C 1 inhibitor deficiency" and completed the "Study on the pathological characteristics of hereditary angioedema complicated with glomerulonephritis". Undertake the research project "Epidemiology and Etiology of IgA Nephropathy" of Academy of Medical Sciences and Union Medical College 1992. He has published more than 60 academic works and won 8 excellent thesis awards. "Clinical application of renal biopsy" won the hospital-level medical achievement award1984; "The value of renal biopsy in the diagnosis, treatment and prognosis of lupus nephritis" won the 1989 hospital-level scientific and technological achievement award. Editor-in-chief of Concise Kidney Diseases, participated in the compilation of 8 monographs including Modern Internal Medicine.