I didn't expect the rest of my body

I cann't believe I'm hiding another kind

Even more unexpected.

It turned out to be a hereditary tumor.

Related to family genes

Check it carefully.

Nine relatives of the whole family had cancer screening.

In the past few months, 28-year-old Jia Shanshan (not her real name) and her family have experienced a roller coaster ride, and a mystery that has plagued this family for many years has finally been uncovered.

One of her indicators is beyond the chart.

Jia Shanshan, a native of northeast China, was diagnosed with thyroid tumor last year. She underwent thyroidectomy and neck lymph node dissection in a local hospital, and the pathological diagnosis was medullary thyroid cancer. The tumor index was already high at the time of postoperative review, and it has been dragging on. Later, lymph node metastasis was found in thoracic mediastinum.

"We looked at her test results and felt something was wrong. One of her indicators, calcitonin, is particularly high. " Deputy Chief Physician of Head and Neck Surgery in a 3A hospital in Zhejiang explained that the calcitonin of normal people is between 0- 15, and that of Jia Shanshan is more than 2,000, which can be basically said to be on the high side. "Medullary thyroid cancer, postoperative calcitonin, must be a metastatic tumor of medullary thyroid cancer.

The incidence of medullary thyroid carcinoma in thyroid malignant tumor is less than 65438 0%, which is a rare tumor. While thinking of medullary thyroid cancer, the doctor also thought of another problem that is easily overlooked: is it possible that the patient's adrenal gland is accompanied by pheochromocytoma? Sure enough, CT showed a 2cm tumor in the patient's left adrenal gland.

"This is a disease with a very low incidence. This is an autosomal dominant genetic disease with familial inheritance. It has two typical symptoms. The patient has medullary thyroid carcinoma with adrenal pheochromocytoma. "

The whole operation lasted for 6 hours and was very successful. Jia Shanshan's adrenal tumor was removed, her thyroid gland was removed, and mediastinal metastatic lymph nodes were cleared. She was discharged smoothly.

Nine people in a family have the same kind of cancer.

After receiving treatment, the story did not end there, and her mother, Ms. Shi, also came to Hangzhou. Because at the suggestion of two doctors, Jia Shanshan's family had a genetic test.

"For so many years, I didn't feel anything wrong. It was last year that I felt palpitations and sweated a lot. Most of the time, I have this symptom in the middle of the night. At this time, I feel my neck is very thick, so I have to sit up, or I feel like I'm going to pass. But this discomfort comes and goes quickly, just for a few seconds. I have taken my blood pressure, and when I feel uncomfortable, it is 180, but I may return to normal after the second and third measurement. "

Examination results and genetic tests show that Ms. Shi also suffers from EN2 syndrome. She is a bilateral adrenal tumor, one side is two centimeters big and the other side is more than 5-6 centimeters.

During the operation, Ms. Shi's bilateral adrenal tumors were removed and most of the tissues were preserved. After the operation, she no longer needs to take medicine for life.

This family is basically related to Ms. Shi: Ms. Shi's mother, Ms. Shi's brother, Ms. Shi's eldest daughter and Ms. Shi's nephew ... After preliminary screening, Ms. Shi and other nine people have been diagnosed with thyroid tumors, and some have had thyroidectomy many years ago. However, adrenal pheochromocytoma has not attracted much attention.

At present, Ms. Shi also informed her immediate family members to have a genetic test to confirm whether it is EN2 syndrome. "At present, only my sister ruled out, which is lucky. I have a little daughter. I'll take her to do it in a few days. Including the children of my eldest daughter. "

The doctor said that if there are unmarried children in the barren woman family who are diagnosed with this hereditary disease, they can also block this inheritance through the technology of the third generation of IVF after they get married and have children.

New Evening News Comprehensive Guangzhou Daily, qianjiang evening news