On the afternoon of 16, Yuan Tao, Bella's attending doctor and CEO of Huayi Music, and his family representatives attended the press conference and made a speech on Bella's condition, announcing that Bella died of clinical cardiac arrest on June+10/6 16: 55, 65438.
At the scene, representatives of the Red Cross attended the press conference and accepted the cornea donated by Bella. It is reported that Bella had a wish to donate corneas before her death, and entrusted her father to sign a volunteer letter for donating corneas on June 9, 65438/KLOC-0, which will be transplanted to patients as soon as possible.
When Hua Shao heard the news of Bella's death, he said that he hadn't seen Bella for a long time. "I have been with students with good voices for three times. It can be said that fate and good voices rise and fall together. This is really a enviable talent. I see the screen is full of memorials. I hope she will continue to sing in heaven. " When talking about his impression of Bella, Hua said little, and the biggest impression was optimism. "Bella has a good grasp of life and works very hard. Every time he performs and sings, he is serious. 」
According to previous media reports, Bella was admitted to the special needs clinic of Peking University Shenzhen Hospital at 65438 on February 26th last year. Recently, her condition suddenly deteriorated. After diagnosis, it was found that cancer cells had metastasized to the brain and lungs, and her family came to the hospital every day for several days.
Bella is very famous in the music circle. She has sung the theme song River of Life of Xiaogang Feng film 1942, the theme song of the TV series Queen of the Palace and all the episodes in the play. He became popular again because he participated in the second season of The Voice of China, and made three appearances in CCTV Spring Festival Evening in 2007, 20 10 and 20 14.
According to media reports, Bella was diagnosed with breast cancer on 20 1 1, and underwent total mastectomy in the same year. A few days ago, Bella's death was reported online, but it was denied by his agency.
Female breasts are composed of skin, fibrous tissue, mammary glands and fat. Breast cancer is a malignant tumor that occurs in mammary epithelial tissue. 99% of breast cancer occurs in women, and only 1% in men.
Breast is not an important organ to maintain human life activities, and cancer in situ is not fatal; However, because breast cancer cells have lost the characteristics of normal cells, the connections between cells are loose and easy to fall off. Once the cancer cells fall off, the free cancer cells can spread to the whole body with blood or lymph, forming metastasis and endangering life. At present, breast cancer has become a common tumor that threatens women's physical and mental health.
Since the late 1970s, the global incidence of breast cancer has been rising. Eight women in the United States will have 1 breast cancer in their lifetime. China is not a country with high incidence of breast cancer, but it is not optimistic. In recent years, the growth rate of breast cancer incidence in China is 1 ~ 2 percentage points higher than that in high-incidence countries. According to the incidence data of breast cancer in 2009 released by the National Cancer Center and the Bureau of Disease Control and Prevention of the Ministry of Health on 20 12, the incidence rate of breast cancer in the national tumor registration area is 1, and the total incidence rate (crude incidence rate) of female breast cancer in China is 42.55/ 1/65438.
Breast cancer has become a major public health problem in today's society. Since the 1990s, the global mortality rate of breast cancer has shown a downward trend. The reasons are: first, the development of breast cancer screening has increased the proportion of early cases; Second, the comprehensive treatment of breast cancer has improved the curative effect. Breast cancer has become one of the most effective solid tumors.
The cause of disease
The cause of breast cancer is not completely clear. It is found that the incidence of breast cancer has certain regularity, and women with high risk factors for breast cancer are prone to breast cancer. The so-called high-risk factors refer to all kinds of risk factors related to the incidence of breast cancer, and the risk factors of most breast cancer patients are called high-risk factors of breast cancer. The Annual Report of Cancer Registration in China shows that the age-specific incidence of female breast cancer is at a low level at the age of 0-24, rising gradually after the age of 25, reaching a peak at the age of 50-54, and gradually decreasing after the age of 55. Family history of breast cancer is a risk factor for breast cancer. The so-called family history refers to the first-degree relatives (mother, daughter, sister) who have breast cancer patients. In recent years, it has been found that breast density has also become a risk factor for breast cancer. The risk factor of breast cancer is early menarche (55 years old); Unmarried, childless, having children late and not breastfeeding; Suffering from benign breast diseases without timely diagnosis and treatment; Hospital biopsy (biopsy) diagnosed atypical hyperplasia of breast; Excessive radiation on the chest; Taking exogenous estrogen for a long time; Postmenopausal obesity; Long-term excessive drinking; Carrying mutant genes related to breast cancer. It should be noted that European and American countries have done a lot of research on susceptibility genes of breast cancer. At present, there are BRCA- 1, BRCA-2, p53, PTEN and so on. Breast cancer associated with these gene mutations is called hereditary breast cancer, accounting for 5% ~ 10% of all breast cancers. Women with the above-mentioned high-risk factors do not necessarily suffer from breast cancer, but can only say that their risk of breast cancer is higher than that of normal people, and the incidence of female breast cancer in China is still low.
clinical picture
Early breast cancer often has no typical symptoms and signs, so it is not easy to attract attention. It is usually found through physical examination or breast cancer screening. The following are typical symptoms of breast cancer.
1, breast lump
80% of breast cancer patients are diagnosed as breast masses for the first time. Patients often inadvertently find breast lumps, mostly single, hard, irregular edges and unsmooth surfaces. Breast cancer is mostly painless mass, and only a few of them are accompanied by dull pain or tingling to varying degrees.
2, * * * overflow
Blood, serous fluid, milk and pus flow out during non-pregnancy period, or milk still flows out after stopping breastfeeding for more than half a year, which is called * * * overflow. There are many reasons for exudation. Common diseases include intraductal tumor, mammary gland hyperplasia, mammary duct dilatation and breast cancer. Unilateral single-hole bloody secretions should be further examined, and more attention should be paid if accompanied by breast masses.
3, skin changes
There are many signs of skin changes caused by breast cancer. The most common thing is that the tumor invades the Cooper's ligament, which connects the breast skin with the deep fascia of the chest, making it short and inelastic, pulling the corresponding skin, resulting in "dimple sign", that is, a small depression appears in the breast skin, like a small dimple. If cancer cells block lymphatic vessels, there will be "orange peel-like changes", that is, many pits appear on the breast skin, just like orange peel. In the late stage of breast cancer, cancer cells infiltrate the skin along lymphatic vessels, glandular ducts or fibrous tissues and grow, forming scattered hard nodules in the skin around the main cancer focus, which are called "skin satellite nodules".
4, * * *, abnormal areola
The tumor is located in or near the deep part of * * *, which can cause the retraction of * * *. When the tumor is far away from * * *, the invasion of the large duct in the breast will be shortened, which can also cause the * * * to retract or elevate. Eczematous cancer, paget's disease of the breast, is characterized by itchy skin, erosion, ulcer, scabbing, desquamation and burning pain, which leads to * * * retraction.
5, axillary lymph node enlargement
More than 1/3 of breast cancer patients admitted to large hospitals have axillary lymph node metastasis. At the initial stage, the axillary lymph nodes on the same side may be enlarged, and the enlarged lymph nodes are hard, scattered and pushable. With the development of the disease, lymph nodes gradually fuse and attach to the skin and surrounding tissues. Metastatic lymph nodes can be felt in advanced clavicle and contralateral armpit.
cheque
In the breast clinic, after the doctor knows the medical history, he will first have a physical examination to check both breasts; It will also be combined with imaging examination, including mammography (mammography), color Doppler ultrasound, and breast magnetic resonance examination (MRI) if necessary. Mammography is the main method of breast cancer screening recommended internationally in recent years. You can find breast cancer that can't be touched by clinical physical examination, which is generally used for women over 40 years old. Female breasts of this age are insensitive to radiation, with limited radiation damage and relatively low breast density. It is easy to find abnormal signs on mammograms. Breast color Doppler ultrasound is harmless to human body, which is ideal for young women and those with dense breasts. Magnetic resonance (MBI) examination can find multiple lesions and small lesions in the center, and it is also an imaging examination method for early diagnosis. The final diagnosis will be based on cytopathology (in a conditional hospital) and histopathological diagnosis, and biopsy will be performed on the basis of abnormal clinical examination, which can be through puncture or surgery. Once cancer cells are found, treatment measures will be taken immediately. If the patient has * * * secretion, we can also carry out some inspection methods for * * * secretion, such as galactoscopy, mammography, cytological smear of secretion, etc.
diagnose
Early detection and diagnosis of breast cancer is the key to improve curative effect. The diagnosis and differential diagnosis of breast cancer should be combined with the patient's clinical manifestations and medical history, physical examination, imaging examination, histopathology and cytopathology examination (in conditional hospitals).
Most patients come to the hospital because they accidentally find breast masses, and a few patients find breast masses or suspicious lesions through regular physical examination or screening. Palpable masses can be diagnosed by needle aspiration biopsy or surgical resection biopsy. If the tumor is not palpable clinically and suspicious lesions are found by imaging examination, biopsy can be taken by imaging examination. Pathological examination is the gold standard for diagnosis of breast cancer.
Breast is located on the surface of human body, so it is not difficult to make a diagnosis. However, according to the statistics of domestic hospitals, there are still many early cases. What delayed the early diagnosis of breast cancer?
1. Female friends don't know enough about medical science knowledge, don't know the clinical characteristics of breast cancer, and lack vigilance against this disease in daily life.
2, early breast cancer is mostly painless tumor, the body can be uncomfortable, neither affecting life nor work.
3. A few women are bound by old ideas, old-fashioned, ashamed of physical examination, and unwilling to go to the hospital for breast examination.
4. Temporary convenience. I listened to some people's nonsense, or I was too superstitious about the diagnosis of a certain instrument, so I let my guard down and stopped further inspection.
Some people have read some books about tumors or are influenced by people around them, so they are afraid of cancer. They are afraid of breast cancer and are afraid to go to the hospital for examination. They don't know that they are caught in a misunderstanding. Whether they have breast cancer or not does not depend on whether they go to the hospital or not. Seeing a doctor can rule out breast cancer and relieve psychological stress. Once breast cancer is diagnosed, it is also found early and can be treated in time.
6, the fast pace of life, busy work, the emergence of new problems, busy dealing with, unable to care about their health, even if there is discomfort, there is no time to go to the hospital, just deal with it. These mistakes have caused many breast cancer patients to delay the opportunity of early diagnosis.
Syndrome differentiation and classification of TCM
1, liver depression and qi stagnation type: see * * * lump, hard, unchanged skin color; Emotional disorder, upset, chest tightness, hypochondriac fullness, breast distension before menstruation, black and yellow tongue coating, and thready pulse.
2. Spleen deficiency and phlegm-dampness type: * * lump with uneven hardness, pits under the armpit, sallow complexion, listlessness, chest distress and abdominal distension, anorexia and loose stool, pale tongue with teeth marks, white and greasy fur and smooth pulse.
3. Impairment of Chong and Ren: menstrual disorder, premenstrual pain, unmarried or childless after marriage, repeated abortion, or postpartum breastfeeding, lumps, pale tongue with thin coating and thready pulse.
4, blood stasis internal resistance type: there are lumps in the milk, the texture is hard, burning pain, the skin color is purple and dark, the boundary is unclear, it can't be pushed open, or the lump is broken, bleeding or oozing yellow water, and the taste is stinky and painful; Boredom, irritability, headache, poor sleep, dry mouth and thirst, yellow urine, dark purple tongue, or ecchymosis, thick and dry yellow fur, heavy and astringent pulse or thready pulse.
5. Deficiency of both qi and blood: there are lumps in the milk, which are uneven, like a pile of millet, rot first and then collapse, with thin sewage, smelly bleeding, pale face, dizziness, short heartbeat, backache and leg weakness, excessive sweating, poor sleep, loose urine, pale tongue with white fur and heavy pulse.
Syndrome differentiation and treatment of TCM
1, Liver-qi stagnation type: treatment: soothing the liver and regulating qi, resolving phlegm and resolving stagnation.
The prescription of Shugan decoction is vinegar Bupleurum 12g, Rhizoma Cyperi 12g, Radix Aucklandiae 12g, Fructus Citri Sarcodactylis 12g, Semen Raphani 20g, Radix Paeoniae Rubra 12g, Radix Angelicae Sinensis/. Rhizoma Atractylodis Macrocephalae 12g, Herba Taraxaci 20g, Prunellae Spica 15g, Shā rotto Katakuri 15g, Semen Citri Tangerinae 12g, and Glycyrrhrizae Radix 6g, decocted in water. Shugan Pills and Pearl Pills are taken orally.
2, spleen deficiency phlegm-dampness type: treatment: spleen and phlegm, swelling and stagnation.
The formula of Jianpi Sanjie Decoction is 20g of Radix Astragali, 20g of Rhizoma Dioscoreae, 0g of Ganoderma lucidum12g, 0g of lentils12g, 0g of Radix Aucklandiae12g, 2g of Fructus Amomi12g, 20g of Radix Codonopsis, 0g of Atractylodis Rhizoma12g and 65438g of Poria. Take Shenfu pills and pellets orally.
3, Chong Ren disorder: treatment: reconcile Chong Ren, regulate qi and relieve depression.
Prescription Tiaochong Decoction, commonly used are Rhizoma Curculiginis 12g, Herba Epimedii 15g, Semen Astragali Complanati 12g, Fructus Leonuri 12g, Fructus Ligustri Lucidi 12g, Ruby 12g and Radix Bupleuri. Decocting Rhizoma Cyperi 12g, Radix Curcumae 12g, Fructus Trichosanthis 20g, Sargassum 12g, Pericarpium Citri Reticulatae Viride 12g, and Shā rotto Katakuri 15g in water. Huanshao Pill and Biejia Pill are taken orally.
4, stasis toxin internal resistance type: treatment: promoting blood circulation and removing blood stasis, clearing away heat and detoxifying.
The prescription of Huayu Jiedu Decoction is Salvia miltiorrhiza 30g, Eupatorium adenophorum 12g, Gan Song 12g, Rhizoma Sparganii 12g, Rhizoma Curcumae 12g, Semen Persicae 12g, Flos Carthami 12g and Radix Paeoniae Rubra 12g. Ochre Pills and Antique can be taken orally.
5, qi and blood deficiency type: treatment: Yiqi Yangxue, auxiliary anti-cancer.
The formula of double tonic soup: Codonopsis pilosula 30g, Pseudostellaria heterophylla 30g, Ganoderma lucidum 15g, Dioscorea opposita 30g, longan 20g, Atractylodes macrocephala 12g, Poria cocos 15g, Angelica sinensis 15g, Astragalus membranaceus 30g, Polygonatum sibiricum 15g and Salvia miltiorrhiza 30g. Take Shiquan Pill and Xiaoaiping orally.
Syndrome differentiation treatment
1, local ulceration and eversion, vegetable pattern, oozing bloody liquid, stale and smelly, green tangerine peel, raw licorice, Fritillaria thunbergii, pangolin scales, angelica dahurica, etc. You can add.
2. When patients with lung metastasis have cough, hemoptysis, shortness of breath and chest pain, Bulbus Fritillariae Cirrhosae, Radix Platycodi, Herba Houttuyniae, Herba et Gemma Agrimoniae and Fructus Trichosanthis can be added as appropriate.
3. For patients with liver metastasis, abdominal distension, yellow eyes and yellow urine, Herba Artemisiae Scopariae, Carapax Trionycis, Herba Patriniae, Rhizoma Polygoni Cuspidati and Zagreb are added.
4, brain metastases with headache, vomiting, add scorpion, centipede, Zaocys, Gastrodia elata, Uncaria, Pinellia ternata, ochre, etc.
A single, biased and proven prescription
1, arrowhead realgar powder, medicinal arrowhead 15g, realgar 3g, nidus vespae 30g, ground, and encapsulated, 3g each time, twice a day.
2. Semen Vaccariae, Radix Ophiopogonis and Flos Lonicerae, 30g each, add 1 2g Yushu Dan and1Kemei tablet, grind into fine powder and mix well. Take 1.5 ~ 3g each time, 4 times a day.
3, 9 grams of Aconitum kusnezoffii, Dafengzi 15 grams, smashed and applied to the affected area.
4, fresh toad skin 6, skin external application patients, 2 tablets a day, for 3 days.
5. Take Huayan Decoction, 6 grams of Radix Rubiae, 6 grams of Semen Sinapis Albae, 30 grams of Poria 15, 30 grams of Flos Lonicerae, 30 grams of Radix Angelicae Sinensis, 30 grams of Radix Astragali, and 0/2 grams of Ginseng 1 dose twice a day.
6. Shā rotto Katakuri 200g, crab shell100g, crab claw100g, ground into fine powder, refined into pills, each pill10g, each pill 1 ~ 2 capsules, twice a day, and taken after meals.
7. Grind noodles with Xingxiao Pill, Olibanum 30g, Myrrha 30g, Musk 3g, realgar powder 3g and Calculus Bovis10g. Mashing 1 yellow rice into pills, drying in the sun, and sealing. 6g per capsule, 1 capsule, twice a day.
8. After surgical radiotherapy, take anti-tumor and anti-inflammatory pills, including bezoar 10g, musk 3g, frankincense 30g, myrrh 30g, notoginseng 20g, codonopsis pilosula 50g, Coicis Semen 50g, Dioscorea bulbifera 30g and pearl powder 20g, and grind them into fine powder, 3g each time and twice a day.
(Chief physician and professor of Zibo Hospital of Traditional Chinese Medicine: Cao Yuancheng)