Zhang is undoubtedly a strong contender for the Nobel Prize. If crispr wins the prize after 2020, Zhang Can will continue to volatilize his talents and expand the application of crispr before then. Some people say that Zhang is not the discoverer of crispr, but just joined in the middle. However, for such a technology, the discoverer occupies at most one position among the three Nobel Prize winners.

Whether a technology or discovery can win the Nobel Prize depends on its significance to the development of the discipline. If it's just a knockout, why didn't anyone say Tarun would win the Nobel Prize? Why can't cre win the Nobel Prize? In ko system, the off-target rate of talen is low, and the tissue specificity of cre is high. At present, both of them have better gene editing effect than crispr. Crispr is popular because it is a convenient crispr_knockout system. Rotate a plasmid stably, then sieve it, and you get ko cells, which was unimaginable before Zhang Feng, okay? This year, Zhang Feng's articles on Nature (crispr system of AAV virus vector) and cell (screening tumor migration-related genes based on whole genome ko of crispr) make me more optimistic about Zhang Feng's development potential in the application of crispr technology. How widely is it used and what are the chances of winning the Nobel Prize?

Secondly, according to the awarding rules of Nobel Prize in history, especially the awarding rules of green fluorescent protein in 2008, we can find that the founder (Martin Scharf), the user (Qian Yongjian) and the creator (Shimomura Xiu) of a technology are equally important for the award. If Zhang Can greatly expands the application of crispr in the next few years (mainly to reduce the missed detection rate), the Nobel Prize of crispr must have Zhang Feng's name.

No application, no matter how good the technology is. By the way, the competition in life sciences is too fierce. . How cruel! ! !