Nanjing East Road Street used to be a field in the northern suburb of Shanghai County. In the 28th year of Daoguang (1848), it was all included in the British Concession. 1953 was established as the fourth office of Laozha District. 1956 Laozha District was merged into Huangpu District and renamed as Nanjing East Road Office in Huangpu District. 1960 merged into Guizhou Road Office and established Nanjing East Road Sub-district Office in Huangpu District. 1August, 988, Nanjing East Road and Changsha Road streets were cancelled and Nanjing East Road streets were established. In March 2007, the three neighborhood committees under the jurisdiction of the former People's Square Street, the former Nanjing East Road Street and the former Jinling East Road Street merged to form the Nanjing East Road Sub-district Office. Convenient traffic

Nanjing East Road Street has three subway lines and 59 bus stops, which is the largest subway transfer and bus distribution point in the city center. Yan 'an East Road section of Yan 'an Elevated Road in the south and Chengdu North Road section of North-South Elevated Road in the west are important traffic passages in Shanghai.