From 65438 to 0999, he received his doctorate from Nankai University and stayed as a teacher. He once worked as a research assistant in the research group of Professor Zhou Qi Lin (an outstanding scholar of Yangtze River Award Program), engaged in chiral catalytic asymmetric synthesis and related drug research, and was hired as an associate professor on 200 1. At the end of 2002, he went to the research group of Professor Q. Cahard, a famous organic fluorine chemist in CNRS, France, to engage in postdoctoral research and carry out research on organic fluorine chemistry and related asymmetric synthesis; In 2004, he was transferred to the research group of Professor Manfred T. Reetz, a famous chemical and molecular biologist of Max Planck Institute in Germany, engaged in asymmetric synthesis and bioorganic chemistry research. In July 2005, he went to Tianjin University and was hired as a professor and doctoral supervisor. At present, the research group is mainly engaged in the design and application of chiral functional molecules, organic fluorine chemistry and related asymmetric synthesis, and the design and synthesis of bio-organic and related chiral drugs.