1982 graduated from Anhui college of traditional Chinese medicine, engaged in clinical research and teaching of neurology for a long time, and mastered the clinical diagnosis and treatment technology of neurology with integrated traditional Chinese and western medicine. He is good at treating headache, dizziness, cervical spondylosis, lumbago and leg pain, epilepsy, myopathy, ADHD, neurosis, facial paralysis, hemifacial spasm and other common diseases. Thousands of cases of hepatolenticular degeneration and other difficult diseases from all over the country have been treated, and epilepsy clinics have been opened. The institute has strong clinical and scientific research capabilities, and has established laboratories for clinical biochemistry, trace elements, high performance liquid and molecular biology. He has published more than 50 academic papers independently or cooperatively in national and provincial magazines such as Chinese Medical Journal and China Journal of Integrated Traditional Chinese and Western Medicine, and participated in writing a monograph on hepatolenticular degeneration.

Chinese name: Hu Jiyuan

Occupation: doctor

Graduation school: Anhui College of Traditional Chinese Medicine

Main results: Study on the mechanism of Gandou decoction in treating hepatolenticular degeneration.

Masterpiece: Effect of Gandou Decoction on Copper Metabolism in Hepatolenticular Degeneration Skin Fibroblast Model

Winning record

I participated in the basic and clinical research on hepatolenticular degeneration of integrated traditional Chinese and western medicine, which was jointly funded by the National Natural Science Foundation of China, state administration of traditional chinese medicine Research Fund, Anhui Science and Technology Commission and Education Department. It was appraised by Anhui Science and Technology Commission 65438-0999 and won the first prize of Anhui Science and Technology Progress in 2000.

Biographical notes

1978.2-1982.11Bachelor of Anhui College of Traditional Chinese Medicine.

1982.11-1992.11resident and teaching assistant in the Department of Neurology, Affiliated Hospital of Anhui College of Traditional Chinese Medicine.

1992.11-1997.11Attending physician and lecturer in neurology, Affiliated Hospital of Anhui College of Traditional Chinese Medicine.

1997.11-1999.12 deputy chief physician and lecturer, Department of Neurology, Institute of Neurology, Anhui University of Traditional Chinese Medicine.

1999.12-2002.12 deputy chief physician and associate professor, Institute of Neurology, Anhui College of Traditional Chinese Medicine.

2002.65438+February to present, chief physician, associate professor and tutor of master students in Department of Neurology, Institute of Neurology, Anhui College of Traditional Chinese Medicine.

research direction

Study on hepatolenticular degeneration, epilepsy, neuroimmune diseases and cerebrovascular diseases.

research subject

Effect of Gandou decoction on copper content, lysosome structure and function of hepatocytes in patients with hepatolenticular degeneration

Evaluation of the degree of liver fibrosis in patients with hepatolenticular degeneration and the intervention effect of copper-expelling therapy

Study on TCM Syndrome Classification and Gene Mutation Diversity of Hepatolenticular Degeneration in China

Thesis monograph

1. Clinical manifestations of Wilson's disease complicated with epilepsy and study on treatment of integrated traditional Chinese and western medicine. Wang Gongqiang. Cheng Nan. Wang Xun. Hong mingfan. Han Yongzhu. Yang renmin. China Journal of Integrated Traditional Chinese and Western Medicine, 09, 2004.

2. Clinical study of six metal poisoning antidotes in the treatment of hepatolenticular degeneration. Anhui medical journal, may 2004.

3. 1200 Ultrasonic manifestations and clinical study of hepatolenticular degeneration Hu Jiyuan, Hong, Su Zengfeng, Cheng Nan, Yang Renmin, chinese journal of clinical neurosciences Journal, 02, 2003.

4. Clinical application of botulinum toxin type A in nervous system diseases.

5. Report of six cases of subacute necrotizing basal ganglia encephalopathy caused by Sophora tonkinensis poisoning Hu Jiyuan, He Guangyuan, Li Kai, Yang Renmin, journal of anhui traditional chinese medical college, 2002, 03.

6. Diagnosis and treatment of chronic cerebral blood supply insufficiency Hu Jiyuan Anhui Medical 2002 03

7. Clinical misdiagnosis of hepatolenticular degeneration. Lu Daping. Wang Gongqiang. He Guangyuan. Cheng Nan. Wang Xun. Hong mingfan. Yang renmin. China medical journal 200 1 1 1.

8. Analysis of misdiagnosis cases of hepatolenticular degeneration in children and observation of treatment. He Guangyuan. Li Kai. Cheng Nan. Wang Xun. Han Yongzhu. Yang renmin. China Journal of Practical Pediatrics 200 1 12.

9. Effect of sodium dimercaptopropane sulfonate on copper metabolism in hepatolenticular degeneration Hu Jiyuan, He Zhichao, Lin Hongxiang, Cheng Nan, Wang Xun, Yang Renmin, Journal of Radioimmunology 2001kloc-0/.

Botulinum toxin type 10.a in the treatment of painful tonic spasm caused by hepatolenticular degeneration. Han Yongzhu. Cai Liangyong. Yang People's China Journal of New Drugs.

1 1. 32 cases of cervical spondylosis of vertebral artery type were treated with water acupuncture at Bailao point Hu Jiyuan, Ren Mingshan, Xu, Yang Renmin, journal of anhui traditional chinese medical college 1998 0 1.

12.HP RPC method combined with ultraviolet absorption derivative method was used to determine serum valproic acid concentration. Xie Xiaomei. Hong mingfan. Yang Anhui People's Hospital 1997 06

13. Preliminary study on identification of "pure Chinese medicine antiepileptic preparation" by HP RPC Hu Jiyuan, Hong, Yang Renmin Anhui Medical 1997 03.

14. Hepatolenticular degeneration with multiple bone cysts 1 case. Journal of Southern Anhui Medical College Yang Renmin 1996 Supplement

15. Clinical and brain CT manifestations of Wilson's disease complicated with epilepsy. Yang renmin. Journal of hong function and stereotactic neurosurgery 1995 No.2

16. Changes of sex hormones in patients with kidney deficiency and impotence before and after tonifying kidney (report of 9 cases) Hu Jiyuan. Journal of anhui traditional chinese medical college 1989 4.

17. Acute cerebral infarction complicated with shoulder-hand syndrome 1 15 cases: review of related factors, Hu Jiyuan, Hong, Li Kai, Yang Renmin, China Clinical Rehabilitation 22, 2004.

18.Dandy-Walker syndrome with cerebral palsy 1 case history. Hu Jiyuan. Yang renmin. Journal of brain and nervous diseases, 2003 0 1.

19. Study on the relationship between Thr935Met mutation of ATP7B gene and clinical phenotype in China. Yang Bin, Hu Jiyuan, Cheng Nan, Yang Guange, Yang Renmin. China Journal of Eugenics and Genetics, 04, 2002.

20. The correlation between the point mutation of Arg778Leu/Gln of ATP7B gene and TCM syndrome types in China hepatolenticular degeneration. Hu Jiyuan. Hong mingfan. Yang China People's Journal of Integrated Traditional Chinese and Western Medicine, 04, 2002.

2 1. Penicillamine allergic reaction and desensitization therapy. Hu Jiyuan. Yang renmin. China Hospital Pharmacy Journal 1998 0 1.

22. TCM syndrome differentiation and classification of hepatolenticular degeneration. Hu Jiyuan. Hu Wenbin. Yang renmin. Journal of anhui traditional chinese medical college 1998 0 1.

23. machado-Joseph disease (report of two families) Yang Renmin. Hu Jiyuan. Wang Xun. Journal of Clinical Neurology 1992, No.2..

CT scan analysis of 24.44 cases of hepatolenticular degeneration. Hu Jiyuan. Journal of Clinical Neurology 199 1, issue 4.

25. Yang Renmin reported 1 case of congenital painless anhidrosis. Hu Jiyuan Journal of Practical Internal Medicine 1988 1 1.

26. 1 case of hypertrophic hard meningitis with epilepsy as the first symptom. Yang renmin. Stone. Hu Jiyuan. Chinese journal of clinical neurosciences magazine, 2003, 0 1.

27. Adrenal leukodystrophy Peripheral Neuropathy 1 Truffle. Cheng Nan. Hu Jiyuan. Li Kai. Yang renmin. Anhui medicine 2003 0 1.

Clinical analysis of clonazepam in the treatment of status epilepticus. Lu Daping. Hu Jiyuan. Yang renmin. Anhui medicine, 2003, March.

29. Study on the function of hypothalamic pituitary ovarian axis in women with hepatolenticular degeneration. Yang renmin. Hu Jiyuan. Lin Lianchu. China Journal of Neurology, June 2000.

30. Prospective comparison of adverse reactions of methylprednisolone and dexamethasone in the treatment of neuroimmune diseases. Wang Xiaoping, Yang Renmin, Hu Jiyuan. Journal of Practical Medicine 19903.

3 1. Study on the mutation of exon 14 of ATP7B gene in patients with hepatolenticular degeneration Hong, Zhang Zhi, Hu Jiyuan, Ren Mingshan, Yang Renmin, Ju. Anhui Medical 19903.

32. Clinical observation on 32 cases of hepatolenticular degeneration treated by Gandou tablet and its effect on trace elements in body fluids Han Yongzhu. Wang Xun. Hu Jiyuan. Hu Wenbin. Yang renmin. Traditional Chinese Medicine Research 1998 04.

33. The clinical effect of sodium dimercaptosuccinate pulse therapy on hepatolenticular degeneration and its influence on trace elements in body fluids Han Yongzhu. Wang Xun. Hu Jiyuan. Hong mingfan. Yang renmin. Journal of Clinical Neurology.

34. Treatment of Wilson's disease with zinc gluconate 3 1 case. Yang renmin. Bao Yuancheng. Hu Jiyuan. Yang. Cai's new medicine and clinic 1989 No.4.

35. Study on mutation of exon 12 of WD gene in China Yan Yongxing, Cheng Nan, Hong, Hu Jiyuan, Yang Renmin, journal of brain and nervous diseases, No.4, 2004.

36. Application value of ECG monitoring in methylprednisolone shock therapy, Hong, Yang Renmin, Hu Jiyuan, Clinical Education of General Medicine, 2004, 1.

37. Experimental observation on the preventive and therapeutic effects of Naoluotong on cerebral ischemia injury. Xu guansun Li Yumei. Hu Jiyuan. China Journal of Basic Medicine of Traditional Chinese Medicine 200 1 02.

38.DNA sequencing confirmed that there was a new frameshift mutation in exon 14 of ATP7B gene in hepatolenticular degeneration. Zhang Zhi, Hong, Ren Mingshan, Hu Jiyuan, Cai, Yang Renmin, Ju,. China Journal of Eugenics and Genetics, 2000,01.

39. The combination of traditional Chinese and western medicine can improve liver cirrhosis and liver function in patients with hepatolenticular degeneration. Hong mingfan. Wang Gongqiang. Yang renmin. Hu Jiyuan. Wang Xiaoping. Lu Daping. China Journal of Integrated Traditional Chinese and Western Medicine,12,2000.

40. Clinical study on treatment of chronic inflammatory demyelinating polyradiculopathy with combination of traditional Chinese and western medicine Ren Mingshan, Yang Renmin, Hu Jiyuan, China Medical Journal 1998 03.

4 1. PCR -SSCP silver staining technique was used to detect the mutation and polymorphism of exon 18 of hepatolenticular degeneration gene. Fan Yuxin, Yu Long, Hu Jiyuan, Gong Ruomu, Xu, Ren Mingshan, Yang Renmin. China Journal of Eugenics and Genetics 1998 02.

42. Changes of nitric oxide and endothelin in plasma and brain tissue of rats with acute cerebral ischemia, Yang Renmin, Han Yongzhu, Hu Jiyuan. Journal of Clinical Neurology.

43. A preliminary study on the mutation of exon 18 of hepatolenticular degeneration gene Ren Mingshan, Yang Renmin, Hu Jiyuan, Ju, Cai Hong. Journal of Clinical Neurology.

44. Clinical observation on treatment of hepatolenticular degeneration with traditional Chinese medicine. Han Yongzhu. Ren Mingshan. Hu Jiyuan journal of traditional chinese medicine 1993 1 1.

45. Treatment of herpes zoster myelitis with combination of traditional Chinese and western medicine. Lou Zongpan. Bao Yuancheng. Hu Jiyuan. Heng. Journal of integrated traditional Chinese and western medicine, 1987, No.7.

46. Study on gallbladder abnormalities and related factors in patients with hepatolenticular degeneration. Lu Daping. Su Zengfeng. Li Kai. Hu Jiyuan. Yang renmin. Chinese journal of practical internal medicine 200 1 1.

47.PCR- restriction enzyme digestion was used to detect the mutation of codon 935 in Wilson's disease. Cheng Nan, Yang Renmin, Hong, Zhang Zhi, Hu Jiyuan, Ren Mingshan, Cai. China Journal of Eugenics and Genetics, 03, 2000.

48. Mutation and polymorphism of exon 18 of ATP7B gene in Wilson disease family. Yang renmin. Ren Mingshan. Fan Yuxin. Hu Jiyuan. Han Yongzhu. Cai Liangyong. Yu Long. China Journal of Eugenics and Genetics 1998 05.

49. Clinical observation on treating 24 cases of chronic cerebral ischemia with Hunaosu capsule Fan Yuxin. Han Yongzhu. Ren Mingshan. Yang renmin. Hu Jiyuan. Li Kai. Hong mingfan. Xu Dao. Journal of Integrated Traditional Chinese and Western Medicine 1997 07.

50. Study on polymorphism and mutation of exon 18 of Honggan Wilson disease gene. Cong Wu Shuang. Ren Mingshan. Zhang zhi Fan Yuxin. Hu Jiyuan. Han Yongzhu. Yang renmin. Chinese journal of clinical neurosciences Journal 19903.

5 1. Effect of Gandou decoction on copper metabolism in hepatolenticular degeneration skin fibroblast model Tang Qiqiang, Yang Renmin, Ren Mingshan, Hong, Cai, Hu Jiyuan, Ding Lili. China Journal of Integrated Traditional Chinese and Western Medicine, 2000,01.

52. Re-discussion on the ultrasonographic features of hepatolenticular degeneration. Wang Jinping. Wang Ningxin. Bao Yuancheng. Yang. Song zhiyun. Xu Dao. Yang renmin. Hu Jiyuan. Journal of anhui traditional chinese medical college 1998 02.

53. Identification of Anovelmissense mutation in hepatolenticular degeneration disease gene, Yang Renmin, Wu Mengchu, Ren Mingshan, Hu Jiyuan, Zhao. Chinese medical journal (English version) 1997 1 1.

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