It is best not to eat red wine and chocolate together;
Try not to eat red wine with chocolate. Scientists believe that they have figured out why chocolate and wine can cause migraine in some people: this is because eating food such as red wine and chocolate can cause microbes in some people's intestines to metabolize nitrite to produce nitric oxide by-products, and these by-products can cause migraine.
In order to find the connection between them, researchers from the University of California, San Diego (UCSD) analyzed 172 oral samples and 1996 fecal samples in the American Intestinal Project database.
The results show that the proportion of microorganisms that can metabolize nitrate in the intestines of migraine patients is relatively high. This discovery tells us that certain foods can cause migraine, such as chocolate and wine, especially foods containing nitrate. We believe that there is a close relationship between people's diet and microbial population in the intestine and the risk of migraine. "
When nitrate enters the body through food and drink, microorganisms in the intestine will contact them and use them as fuel. But nitrate will not disappear, because microorganisms will also produce their own waste, called nitrite, which will eventually become nitric oxide in our blood.
Nitric oxide is not completely without benefits. It can dilate our blood vessels. Thus improving cardiovascular health, but some people think that this expansion will increase a person's risk of migraine.
In fact, patients with chest pain or heart disease often take drugs containing nitrate, but 80% patients will have side effects of headache. We don't know whether this is related to microorganisms in the intestine.
By sequencing the microorganisms in the samples, the researchers used bioinformatics methods to identify specific types of microbial genes in different individuals.
The results show that there are high-level genes encoding nitrate ion, nitrate and nitric oxide metabolism in the samples of individuals with migraine. But researchers also admit that more work is needed to prove this hypothesis.