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When was the problem vaccine?
Recently, the problem vaccine time in Shandong Province has been heated up, and various opinions are increasing day by day. So what is the so-called problem vaccine? Is the panic of mothers unnecessary? Cradle network directly hit the whole story of Shandong problem vaccine incident, and gave you the most comprehensive report at the first time.

20 16 March 18

Some media broke out that since 20 10, Pangmouwei's mother and daughter in Jinan, Shandong Province were suspected of illegally operating vaccines, illegally purchasing 25 kinds of second-class vaccines for children and adults, and selling them to the whole country 18 provinces and cities without strict cold chain storage and transportation, involving 570 million yuan.

20 16 March 19

The US Food and Drug Administration in Shandong announced: According to the information obtained by the US Food and Drug Administration in Jinan in assisting the public security organs to detect the illegal operation of vaccines such as Pang Mou, the online clues 107 and offline clues 193 for providing vaccines and biological products to Pang Mou and other places were sorted out, involving 24 provinces and cities across the country.

The 24 provinces and cities involved are: Anhui, Beijing, Fujian, Gansu, Guangdong, Guangxi, Guizhou, Hebei, Henan, Heilongjiang, Hubei, Jilin, Jiangsu, Jiangxi, Chongqing, Zhejiang, Sichuan, Shaanxi, Shanxi, Shandong, Hunan, Liaoning, Inner Mongolia and Xinjiang.

2065438+March 20, 2006

The US Food and Drug Administration in Shandong verified the list of vaccine varieties seized by Pang in the case of illegal operation of vaccines provided by the police, and found that there were 2 kinds of vaccines 1 species, 2 kinds of immunoglobulins, and therapeutic biological products1species. The specific list is as follows:

12 vaccine has no class I vaccine, and all are class II vaccines:

Freeze-dried rabies vaccine for human use (Vero cells)

Polio eradication vaccine

Haemophilus influenzae type b conjugate vaccine

Live attenuated meningococcal B vaccine

Live attenuated mumps vaccine

Freeze-dried inactivated Japanese encephalitis vaccine (vero cells)

Recombinant hepatitis B vaccine (CHO cells, Hansenula)

Group A and Group C meningococcal conjugate vaccine

ACYW 135 meningococcal polysaccharide vaccine

Attenuated varicella vaccine

Oral rotavirus live vaccine

Inactivated hepatitis A vaccine (human diploid cells)

Two kinds of immunoglobulins:

Rabies human immunoglobulin

Hepatitis B human immunoglobulin

1 therapeutic biological products:

Bacterial lysate

What are the problems with the problem vaccine?

Vaccine, this is the child who has to be vaccinated from birth! It stimulates the human immune system to produce antibodies through the "antigen" contained in it, protecting human health. The key to any vaccine is its "antigen" part. In order to ensure the biological activity of antigens, most vaccines should be kept at a constant temperature of 2 ~ 8℃. Whether it is high temperature or freezing, or even long-term illumination, it may affect the efficacy of the vaccine, and even lead to inactivation and failure of the vaccine.

Some vaccines sold by Pang belong to temporary vaccines, and there are only two freezers for freezing ice cubes in the warehouse where the vaccines are stored. Pang put the whole vaccine naked in a warehouse without refrigeration. When he got off the assembly line, he distributed vaccines in foam boxes, put them in ice cubes, wrapped them and sent them to all parts of the country through express delivery companies. At the scene where Pang's mother and daughter were arrested, it was raining lightly, and the temperature was several degrees Celsius lower than usual. But the thermometer in the warehouse where the vaccine is stored shows that the room temperature is close to 14℃. The biggest cause of panic in the news exposure of illegal vaccines is that vaccines are not preserved in the cold chain and sold everywhere.

Is the question vaccine fatal?

Wang Yuedan, deputy director of the Department of Immunology in peking university health science center, commented, "This is killing people." So is it really fatal to inject the problem vaccine?

Inoculation of vaccines or expired vaccines that have not been stored at 2℃-8℃ and transported by cold chain, the primary risk is that the immunity is invalid, which will lead to the failure of normal immunity. The vaccines involved this time include "vaccines against meningitis, chickenpox and polio in children and vaccines against influenza, rabies and hepatitis A in adults" and so on. And injected with an ineffective vaccine, so you don't have the immunity you deserve. Of course, you will face a higher possibility of death! For example, rabies, a deadly infectious disease, could have been prevented by vaccination. However, vaccination with problematic vaccines leads to ineffective immunity, and the vaccinator may be infected and die.

Vaccinate the baby?

Parents who have doubts can directly choose a trusted institution to replant or wait for vaccination. After the case is further clarified, they can decide whether to replant the corresponding vaccine by comparing the inoculation point found with the vaccination history of the child.

Based on the principle of prudence, if parents are still uneasy about the second-class vaccine, then wait. This time delay generally does not affect the effectiveness of the vaccine. It's best to wait until things are clear and try to avoid those problem vaccines.

In addition, regular epidemic prevention centers in first-tier cities where vaccine management has been relatively strict basically do not have to worry about the existence of problematic vaccines. You can choose an epidemic prevention institution that you think is reliable enough to vaccinate.

Who started it?

As the main suspect in this case, Pang had a "criminal record" of illegally operating vaccines. Pang is a 47-year-old doctor at Peony People's Hospital in Heze City, Shandong Province. He runs an epidemic prevention clinic in Dongcheng District of the city. In 2009, Pang was sentenced to three years in prison, suspended for five years, and fined 500,000 yuan for illegally operating the second-class vaccine, with only one person involved reaching 4.89 million yuan. However, during the probation period, Pang "returned to his old job" and made the business of illegally operating vaccines bigger and more rampant. This time, in the warehouse rented by Pang, more than 20,000 vaccines such as meningococcal, chickenpox and polio for children and 25 vaccines such as influenza, rabies and hepatitis A for adults were seized 100.

From 20 10, for more than five years, Ms. Pang and her daughter bought 25 kinds of vaccines for human use (some for clinical use) from more than 70 salesmen or vaccine distributors of pharmaceutical companies in Shaanxi, Chongqing, Jilin and other provinces and cities 10, and then sold them to Hubei, Anhui, Guangdong, Henan, Sichuan and other places at higher prices. The accumulated transaction amount is as high as 570 million yuan, including 260 million yuan paid and 3 1 10,000 yuan received.

Why can Pang commit such a large-scale crime? Why was the first case only sentenced to three years in prison and suspended for five years? Why didn't you repent during the probation period, but instead intensified and made more crazy behavior? During these five years, how much harm has the problem vaccine brought to society, families and children themselves? How will the vaccine that has already flowed out be finally solved? We will follow up this report further.