1. Academic recognition: The University of Manila is a comprehensive university recognized and authorized by the Philippine government. It has a variety of colleges and disciplines such as law, business, engineering and science, and offers undergraduate and postgraduate degrees. City University of Manila is a municipal university, offering bachelor's degrees and career-related vocational and technical learning opportunities.

2. Academic reputation and ranking: The University of Manila enjoys a high reputation in the Philippines and internationally and is considered as one of the best universities in the Philippines. The teaching and research of all subjects are of high level. City University of Manila also has a good local reputation, but its academic reputation and international ranking are low.